Pioglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARγ, EC50 = 500-600 nM) over PPAR⍺. It also a thiazolidinedione (TZD) anti-diabetic.
Pioglitazone is a selective thiazolidinedione-based PPARγ agonist with EC50 value of 0.69μM for activating transcriptional activity of PPARγ and occupied PPARγ up to 90% at concentration of 100μM. Pioglitazone also showed weak activation effect on hPPARα[1][2]. Pioglitazone exhibited minimum effective dose at 300μM/kg for significant reduction in blood glucose in ob/ob mice[1]. Pioglitazone is used as an antidiabetic agent that improves hyperglycaemia and hyperlipidaemia in obese and diabetic animals through its action of reduction in hepatic and peripheral insulin resistance[2].
作用机制
Pioglitazone exhibited competition binding to PPARγ as a high affinity ligand.[1]
Iran, Islamic Republic of
... 展开 >>
Department of psychiatry, Roozbeh psychiatric hospital, Tehran University of medical sciences
Tehran, Iran, Islamic Republic of, 14479 收起 <<
United States, Arizona
... 展开 >>
Carl T. Hayden VA Medical Center
Phoenix, Arizona, United States, 85012
United States, California
USC-Keck School of Medicine
Los Angeles, California, United States, 90033
University of California San Diego-San Diego VA Medical Center
San Diego, California, United States, 92161
United States, District of Columbia
Georgetown University
Washington, District of Columbia, United States, 20007
United States, Louisiana
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
United States, New York
SUNY Health Science Center
Brooklyn, New York, United States, 11203
United States, Tennessee
University of Tennessee
Memphis, Tennessee, United States, 38163
United States, Texas
Texas Diabetes Institute
San Antonio, Texas, United States, 78207 收起 <<
Iran, Islamic Republic of
... 展开 >>
Diabetes Clinic, Vali-Asr Hospital, Tehran University of Medical Sciences
Tehran, Iran, Islamic Republic of, 13145-784 收起 <<
Brazil
... 展开 >> Centro de Hematologia e Hemoterapia - Universidade Estadual de Campinas
Recruiting
Campinas, SP, Brazil, 13083-868
Contact: Katia B Pagnano, MD 55-19-35218740 kborgia@unicamp.br
Contact: Márcia T Delamain, MD 55-19-35218740 marciatd@unicamp.br
Principal Investigator: Katia B Pagnano, MD
Sub-Investigator: Márcia T Delamain, MD
Sub-Investigator: Gislaine O Duarte, MD
Sub-Investigator: Erich V De Paula, MD
Sub-Investigator: Carmino A De Souza, MD 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
United States, Virginia
INOVA Fairfax Hospital
Falls Church, Virginia, United States, 22042 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
United States, Iowa
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
United States, Massachusetts
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
United States, Minnesota
Masonic Cancer Center, University of Minnesota
Minneapolis, Minnesota, United States, 55455
United States, New York
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Columbia University Medical Center
New York, New York, United States, 10032
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065
Weill Medical College of Cornell University
New York, New York, United States, 10065
United States, South Carolina
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
United States, Texas
MD Anderson Cancer Center
Houston, Texas, United States, 77030
United States, Wisconsin
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792
Canada, British Columbia
BC Cancer Agency (Vancouver Cancer Centre)
Vancouver, British Columbia, Canada, V5Z 4E6
Italy
European Institute of Oncology
Milano, Italy, 20141 收起 <<
Korea, Republic of
... 展开 >>
Pusan National University Hospital
Recruiting
Busan, Korea, Republic of, 602-739
Contact: Sang Soo Kim, MD., PhD. +82-51-240-7228 drsskim7@gmail.com
Contact: Jong Ho Kim, MD. +82-51-240-7983 bedaya@hanmail.net 收起 <<
Iran, Islamic Republic of
... 展开 >>
Diabetes Clinic, Vali-Asr Hospital, Tehran University of Medical Sciences
Tehran, Iran, Islamic Republic of, 13145-784 收起 <<
United States, Texas
... 展开 >>
Baylor Clinics
Houston, Texas, United States, 77030
Baylor College of Medicine
HOuston, Texas, United States, 77030 收起 <<
Terminated(Study never publish... 展开 >>ed; terminated early due to low accrual.) 收起 <<
-
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
United States, New York
New York University
New York, New York, United States, 10016 收起 <<
Major Depressive Disorder
... 展开 >> Insulin Resistance 收起 <<
Phase 4
Completed
-
United States, California
... 展开 >>
Stanford University Department of Psychiatry & Behavioral Sciences
Palo Alto, California, United States, 94305 收起 <<
Korea, Republic of
... 展开 >>
Chagwon, Korea, Republic of
Daegu, Korea, Republic of
Daejeon, Korea, Republic of
Gwangju, Korea, Republic of
Gyeonggi-do, Korea, Republic of
Jeonju, Korea, Republic of
Seoul, Korea, Republic of
Ulsan, Korea, Republic of
Wonju, Korea, Republic of 收起 <<
Switzerland
... 展开 >> Nephrology Service Department of Medicine CHUV
Recruiting
Lausanne, Vaud, Switzerland, 1011
Contact: Anne Zanchi, MD 41 21 314 11 54 azanchidel@hotmail.com
Principal Investigator: Anne Zanchi, MD 收起 <<
Bangladesh
... 展开 >> Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM)
Dhaka, Bangladesh, 1000 收起 <<
United States, Colorado
... 展开 >>
University of Colorado
Aurora, Colorado, United States, 80045
United States, Michigan
University of Michigan
Ann Arbor, Michigan, United States, 48109
United States, Pennsylvania
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
United States, Texas
University of Texas MD Anderson Cancer Center
Houston, Texas, United States, 77030 收起 <<
Korea, Republic of
... 展开 >>
Busan Saint Mary's Medical Center
Busan, Korea, Republic of
Dong-AUniversity Medical Center
Busan, Korea, Republic of
Inje University Baik Hospital
Busan, Korea, Republic of
Kosin University Hospital
Busan, Korea, Republic of
Pusan National University Hospital
Busan, Korea, Republic of
Changwon Fatima Hospital
Changwon, Korea, Republic of
Daegu Catholic University Medical Center
Daegu, Korea, Republic of
Keimyung University Dongsan Medical Center
Daegu, Korea, Republic of
Kyungbuk National Universtiy Hospital
Daegu, Korea, Republic of
Chonnam National University Hospital
Gwangju, Korea, Republic of
Chosun University Hospital
Gwangju, Korea, Republic of
Chonbuk National University Hospital
Jeonju, Korea, Republic of
Gyeongsang National University Hospital
Jinju, Korea, Republic of
Masan Samsung Medical Center
Masan, Korea, Republic of
Ulsan University Hospital
Ulsan, Korea, Republic of 收起 <<
United States, Massachusetts
... 展开 >>
Dana-Farber Cancer Institute
Boston, Massachusetts, United States, 02115
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02215 收起 <<
United States, Texas
... 展开 >>
University of Texas at Arlington
Recruiting
Arlington, Texas, United States, 76010
Contact: Paul J Fadel, PhD 817-272-4653 paul.fadel@uta.edu
UT Southwestern
Recruiting
Dallas, Texas, United States, 75390
Contact: Robert Toto, MD 214-648-2744 Robert.Toto@UTSouthwestern.edu 收起 <<
United States, Georgia
... 展开 >>
Atlanta VA Medical Center
Recruiting
Decatur, Georgia, United States, 30033
Contact: David Guidot, MD 404-321-6111 ext 6935
Principal Investigator: David Guidot, MD
Sub-Investigator: Ashish Mehta, MD, MSc 收起 <<
China, Beijing
... 展开 >>
Beijing, Beijing, China
China, Hubei
Wuhan, Hubei, China
China, Liaoning
Dalian, Liaoning, China
Shenyang, Liaoning, China
China, Shandong
Jinan, Shandong, China
Qingdao, Shandong, China
Tai'an, Shandong, China
Taian, Shandong, China
China, Tianjin
Tianjin, Tianjin, China
Hong Kong
Sai Ying Pun, Hong Kong
Sha Tin, Hong Kong 收起 <<
Terminated(Unanticipated delay... 展开 >>s due to sterilization/stabilization testing of GLP-1.) 收起 <<
-
United States, Georgia
... 展开 >>
Grady Memorial Hospital
Atlanta, Georgia, United States, 30303
Emory University Hospital
Atlanta, Georgia, United States, 30322 收起 <<
United States, Texas
... 展开 >>
UT Southwestern Medical Center - Center for Mineral Metabolism
Recruiting
Dallas, Texas, United States, 75390-8885 收起 <<
United States, Texas
... 展开 >>
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
Dallas, Texas, United States, 75390 收起 <<
United States, Texas
... 展开 >>
Texas Diabetes Institute
Recruiting
San Antonio, Texas, United States, 78229-3900
Contact: Muhammad Abdul-Ghani, MD, PhD 210-567-2391 ABDULGHANI@UTHSCSA.EDU
Contact: Curtiss Puckett, PA (210) 358 7200 Curtiss.Puckett@uhs-sa.com
Principal Investigator: Ralph DeFronzo, MD 收起 <<
China, Guangdong
... 展开 >>
endocrinology department of the first affiliated hospital of Sun Yat-sen University
Recruiting
Guangzhou, Guangdong, China, 510080
Contact: Yanbing Li, MD,PhD 8602087334331 easd04lyb@126.com
Principal Investigator: Yanbing Li, MD,PhD 收起 <<
Type 2 Diabetes With Non-alcoh... 展开 >>olic Fatty Liver (NAFLD) 收起 <<
Phase 4
Completed
-
Korea, Republic of
... 展开 >>
Yonsei University College of Medicine, Department of internal Medicine, Division of Endocrinology, Severance Hospital, Diabetes Center
Seoul, Korea, Republic of, 03722 收起 <<
United States, Arizona
... 展开 >>
Clinical Research Unit
Recruiting
550 East Orange Street, Arizona, United States, 85287
Contact: Christian Meyer, MD (480) 965-2473 Christian.Meyer@asu.edu 收起 <<
United States, Arkansas
... 展开 >>
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
United States, Kentucky
University of Kentucky
Lexington, Kentucky, United States, 40536 收起 <<
United States, California
... 展开 >>
Ucsf Aids Crs (801)
San Francisco, California, United States, 94110
United States, Illinois
Northwestern University CRS (2701)
Chicago, Illinois, United States, 60611
United States, New Jersey
New Jersey Medical School-Adult Clinical Research Ctr. CRS (31477)
Newark, New Jersey, United States, 07103
United States, New York
Cornell CRS (7804)
New York, New York, United States, 10011
NY Univ. HIV/AIDS CRS (401)
New York, New York, United States, 10016
AIDS Care CRS (1108)
Rochester, New York, United States, 14642
United States, Ohio
Metro Health CRS (2503)
Cleveland, Ohio, United States, 44109
United States, Virginia
Virginia Commonwealth Univ. Medical Ctr. CRS (31475)
Richmond, Virginia, United States, 23219 收起 <<
United States, Maryland
... 展开 >>
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Bethesda, Maryland, United States, 20892 收起 <<
United States, California
... 展开 >>
University of California, San Diego
San Diego, California, United States, 92103
University of California, San Francisco
San Francisco, California, United States, 94143
United States, Indiana
Indiana University
Indianapolis, Indiana, United States, 46202
United States, Missouri
St. Louis University
Saint Louis, Missouri, United States, 63110
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27710
United States, Ohio
Case Western Reserve University
Cleveland, Ohio, United States, 44109
United States, Virginia
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
United States, Washington
University of Washington
Seattle, Washington, United States, 98195 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
United States, Virginia
Fairfax Hospital
Falls Church, Virginia, United States, 22046 收起 <<
France
... 展开 >> CHR Annecy
Annecy, France
Institut Bergonié
Bordeaux, France
CH Versailles
Le Chesnay, France
CHU Lille
Lille, France
IPC
Marseille, France
CHU archet 1
Nice, France
St Louis
Paris, France
CHU Poitiers
Poitiers, France
CHU Purpan
Toulouse, France 收起 <<
United States, California
... 展开 >>
Artesia, California, United States
Norwalk, California, United States
Santa Ana, California, United States
Santa Monica, California, United States
United States, Florida
Panama City, Florida, United States
United States, Rhode Island
Cranston, Rhode Island, United States
United States, Texas
Dallas, Texas, United States
Houston, Texas, United States 收起 <<
United States, Oregon
... 展开 >>
Oregon Health & Science University
Recruiting
Portland, Oregon, United States, 97239
Principal Investigator: Bethany J. Klopfenstein, MD 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center, 9000 Rockville Pike
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov 收起 <<
Terminated(This study is being... 展开 >> discontinued based on data suggesting that none of the doses tested demonstrated both glycemic & body fluid benefits vs. the comparitor) 收起 <<
United States, Massachusetts
... 展开 >>
Joslin Diabetes Center
Boston, Massachusetts, United States, 02215
United States, Minnesota
International Diabetes Center
Minneapolis, Minnesota, United States, 55416
United States, Nevada
Palm Medical Group
Las Vegas, Nevada, United States, 89148
United States, North Carolina
University of North Carolina Diabetes Care Center
Durham, North Carolina, United States, 27713
United States, Washington
Rockwood Clinic
Spokane, Washington, United States, 99202 收起 <<
Italy
... 展开 >> Department of Geriatrics and Metabolic Diseases
Active, not recruiting
Naples, Italy, 80138
Katherine Esposito
Recruiting
Naples, Italy, 80138
Contact: Maria Ida Maiorino, MD mariaida.maiorino@unina2.it
Sub-Investigator: Giuseppe Bellastella, MD 收起 <<
United States, Alabama
... 展开 >>
Huntsville, Alabama, United States
Muscle Shoals, Alabama, United States
United States, California
Chino, California, United States
Los Angeles, California, United States
Spring Valley, California, United States
Walnut Creek, California, United States
United States, Florida
Miami, Florida, United States
New Port Richley, Florida, United States
Palm Harbor, Florida, United States
Pembroke Pines, Florida, United States
United States, Georgia
Marietta, Georgia, United States
United States, Illinois
Chicago, Illinois, United States
United States, Indiana
Indianapolis, Indiana, United States
United States, Michigan
Grand Rapids, Michigan, United States
United States, Ohio
Cincinnati, Ohio, United States
Kettering, Ohio, United States
Tiffin, Ohio, United States
United States, Oklahoma
Oklahoma City, Oklahoma, United States
United States, Oregon
Eugene, Oregon, United States
Portland, Oregon, United States
United States, South Carolina
Greer, South Carolina, United States
United States, Texas
Corpus Christi, Texas, United States
Houston, Texas, United States
San Antonio, Texas, United States 收起 <<
Taiwan
... 展开 >> Division of Cardiology, Department of Internal Medicine and Department of Medical Imaging, National Taiwan University Hospital
Recruiting
Taipei, Taiwan, 100
Contact: Tzung-Dau Wang, MD, PhD 886-2-2312-3456 ext 5632 tdwang@ha.mc.ntu.edu.tw
Principal Investigator: Tzung-Dau Wang, MD, PhD
Sub-Investigator: Wen-Jeng Lee, MD 收起 <<
United States, Florida
... 展开 >>
North Florida/South Georgia Veterans Health System, Gainesville, FL
Gainesville, Florida, United States, 32608
United States, Texas
South Texas Health Care System, San Antonio, TX
San Antonio, Texas, United States, 78229 收起 <<
France
... 展开 >> Martine GARDEMBAS
Recruiting
Angers, France
Contact: Martine GARDEMBAS 02.41.35.44.75 MaGardembas@chu-angers.fr
Pascale CONY.MAKHOUL
Recruiting
Annecy, France
Contact: Pascale CONY.MAKHOUL 04.50.63.64.31 pconymakhoul@ch-annecygenevois.fr
Thorsten BRAUN
Recruiting
Bobigny, France
Contact: Thorsten BRAUN 01.48.95.54.58 Thorsten.braun@avc.aphp.fr
Etienne
Recruiting
Bordeaux, France
Contact: Gabriel Etienne 05.56.33.04.76 G.Etienne@bordeaux.unicancer.fr
CHU Côte de Nacre
Not yet recruiting
Caen, France
Contact: Hyacynthe Johnson-Ansah 02.31.27.25.39 Johnsonansah-a@chu-caen.fr
CHU Estaing
Not yet recruiting
Clermont-Ferrand, France
Contact: Marc BERGER mberger@chu-clermontferrand.fr
CH Henri Mondor
Recruiting
Créteil, France
Contact: ROY Lydia
Rousselot
Recruiting
Le Chesnay, France
Contact: Philippe Rousselot 01.39.63.89.09 phrousselot@ch-versailles.fr
CHU Lille
Recruiting
Lille, France
Contact: COITEUX Valérie
CHU de LIMOGES
Not yet recruiting
Limoges, France
Contact: Amélie PENOT 05.55.05.66.42 Amelie.penot@chu-limoges.fr
Franck NICOLINI
Recruiting
Lyon, France
Contact: Franck NICOLINI 04.72.11.74.01 franck.nicolini@chu-lyon.fr
Institut P Calmette
Recruiting
Marseille, France
Contact: CHARBONNIER Aude
Viviane DUBRUILLE
Recruiting
Nantes, France
Contact: Viviane DUBRUILLE 02.40.08.32.71 Viviane.dubruille@chu-nantes.fr
Hopital l'Archet
Not yet recruiting
Nice, France
Contact: Laurence LEGROS 04.92.03.58.41 legros.l@chu-nice.fr
Eric JOURDAN
Recruiting
Nimes, France
Contact: Eric JOURDAN 04.66.68.32.31 eric.jourdan@chu-nimes.fr
Hôpital La Source
Recruiting
Orléans, France
Contact: BENBRAHIM Omar
Delphine REA _St louis
Recruiting
Paris, France
Contact: Delphine REA 01.42.49.96.49 delphine.rea@aphp.fr
Simona LAPUSAN_St Antoine
Recruiting
Paris, France
Contact: Simona LAPUSAN 01.49.28.34.42 Simona.lapusan@sat.aphp.fr
Cayssials
Recruiting
Poitiers, France
Contact: Emilie Cayssials : 05.49.44. 44.72 e.cayssials@chu-poitiers.fr
CHU de Rennes - Pontchaillou
Recruiting
Rennes, France
Contact: ESCOFFRE-BARBE Martine
Hôpital René Huguenin
Not yet recruiting
Saint-Cloud, France
Contact: Sylvie GLAISNER 01.47.11.15.30 Sylvie.glaisner@curie.net
Institut Universitaire contre le Cancer
Not yet recruiting
Toulouse, France
Contact: Françoise HUGUET 05.31.15.63.56 Huguet.françoise@iuct-oncopole.fr
CHU Tours
Not yet recruiting
Tours, France
Contact: DARTIGEAS Caroline 收起 <<
Type 2 Diabetes Mellitus
... 展开 >> Diabetes Mellitus, Type II 收起 <<
Phase 2
Phase 3
Completed
-
Japan
... 展开 >>
Chubu region, Japan
Chugoku region, Japan
Hokkaido region, Japan
Kanto region, Japan
Kinki region, Japan
Kyushu region, Japan
Tohoku region, Japan 收起 <<
Terminated(The development pro... 展开 >>gram has been terminated) 收起 <<
-
United States, California
... 展开 >>
Research Site
Pasadena, California, United States
United States, District of Columbia
Research Site
Washington, District of Columbia, United States
United States, Florida
Research Site
Gainesville, Florida, United States
Research Site
Miami, Florida, United States
Research Site
Orlando, Florida, United States
United States, Georgia
Research Site
Augusta, Georgia, United States
Research Site
Columbus, Georgia, United States
United States, Louisiana
Research Site
New Orleans, Louisiana, United States
United States, Nevada
Research Site
Reno, Nevada, United States
United States, New York
Research Site
Flushing, New York, United States
United States, North Carolina
Research Site
Durham, North Carolina, United States
United States, Ohio
Research Site
Cleveland, Ohio, United States
Research Site
Columbus, Ohio, United States
United States, Oklahoma
Research Site
Tulsa, Oklahoma, United States
United States, Pennsylvania
Research Site
Cheswick, Pennsylvania, United States
Research Site
Philadelphia, Pennsylvania, United States
United States, Tennessee
Research Site
Nashville, Tennessee, United States
United States, Texas
Research Site
Midland, Texas, United States
Research Site
San Antonio, Texas, United States
United States, Washington
Research Site
Gig Harbor, Washington, United States
Research Site
Seattle, Washington, United States 收起 <<
United States, Louisiana
... 展开 >>
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70809 收起 <<
United States, Alabama
... 展开 >>
University of Alabama at Birmingham
Recruiting
Birmingham, Alabama, United States, 35294
Contact: Beatriz Hanaoka, MD 205-996-0843 bhanaoka@uabmc.edu
Contact: Laura E Tudor 205-934-4021 ltudor@uabmc.edu 收起 <<
Hong Kong
... 展开 >> Queen Mary Hospital and Tung Wah Hospital
Hong Kong, Hong Kong, 0000
Queen Mary Hospital, Tung Wah Hospital
Hong Kong, Hong Kong, 0000 收起 <<
United States, New Jersey
... 展开 >>
Novartis Pharmaceuticals
East Hanover, New Jersey, United States, 07936
Germany
Investigative Centers
Nurnberg, Germany 收起 <<
Korea, Republic of
... 展开 >>
Yonsei University College of Medicine, Department of Internal Medicine, Division of Endocrinology, Severance Hospital, Diabetes Center
Not yet recruiting
Seoul, Korea, Republic of, 03722
Contact: Bong Soo Cha, MD +82-2-2228-1932 bscha@yuhs.ac 收起 <<
Japan
... 展开 >> GSK Investigational Site
Hokkaido, Japan, 051-0005
GSK Investigational Site
Ibaraki, Japan, 311-0113
GSK Investigational Site
Kanagawa, Japan, 224-0024
GSK Investigational Site
Tokyo, Japan, 125-0054
GSK Investigational Site
Tokyo, Japan, 130-0004 收起 <<
Germany
... 展开 >> Schön Klinik Starnberger See
Recruiting
Berg, Germany, 82335
Contact: Christian Straka, PD MD
Principal Investigator: Christian Straka, PD MD
Gemeinschaftspraxis Dres. med. J. Wilke u. H. Wagner
Recruiting
Fürth, Germany, 90766
Contact: Jochen Wilke, MD
Principal Investigator: Jochen Wilke, MD
Universitätsklinikum Schleswig-Holstein, II Medizin, Sekt. f. Stammzell- u. Immuntherapie
Recruiting
Kiel, Germany, 24105
Contact: Martin Gramatzki, Prof. MD
Principal Investigator: Martin Gramatzki, Prof. MD
Klinikum d. Universität München, Med. Klinik u. Poliklinik IV, Abt. H/O
Recruiting
München, Germany, 80336
Contact: Christian Adam, MD
Principal Investigator: Christian Adam, MD
Gemeinschaftspraxis Hämato/Onkologie
Recruiting
München, Germany, 81241
Contact: Burkhard Schmidt, MD
Principal Investigator: Burkhard Schmidt, MD
University of Regensburg
Recruiting
Regensburg, Germany, 93053
Contact: Albrecht Reichle, Professor albrecht.reichle@klinik.uni-regensburg.de
Sub-Investigator: Matthias Grube, MD
Sub-Investigator: Joachim Hahn, MD
Sub-Investigator: Stephanie Mayer, MD
Sub-Investigator: Martin Vogelhuber, MD
Sub-Investigator: Christina Hart, MD
Sub-Investigator: Karin Landfried, MD
Sub-Investigator: Marco Petronio, MD
Sub-Investigator: Dagmar Roll, MD
Sub-Investigator: Tanja Zilch, MD 收起 <<
Japan
... 展开 >>
Hirosaki-shi, Aomori, Japan
Kisaratsu-shi, Chiba, Japan
Matsuyama-shi, Ehime, Japan
Fukuoka-shi, Fukuoka, Japan
Kitakyushu-shi, Fukuoka, Japan
Kurume-shi, Fukuoka, Japan
Fukuyama-shi, Hiroshima, Japan
Hiroshima-shi, Hiroshima, Japan
Sapporo-shi, Hokkaido, Japan
Koga-shi, Ibaraki, Japan
Yokohama-shi, Kanagawa, Japan
Kumamoto-shi, Kumamoto, Japan
Miyazaki-shi, Miyazaki, Japan
Suita-shi, Osaka, Japan
Koshigaya-shi, Saitama, Japan
Otsu-shi, Shiga, Japan
Chiyoda-ku, Tokyo, Japan
Chuo-ku, Tokyo, Japan
Itabashi-ku, Tokyo, Japan
Meguro-ku, Tokyo, Japan
Minato-ku, Tokyo, Japan
Ohta-ku, Tokyo, Japan
Shinjuku-ku, Tokyo, Japan
Toyama-shi, Toyama, Japan
Shimonoseki-shi, Yamaguchi, Japan 收起 <<
Germany
... 展开 >> Diabetologische Schwerpunktpraxis Dr. Lorra / Dr. Bonnermann
Bochum, Germany, 44869
Zentrum für klinische Studien Dresden, GWT-TUD GmbH
Dresden, Germany, 01307
Gemeinschaftspraxis Partner der Gesundheit
Essen, Germany, 45355
IKFE Institute for Clinical Research and Development
Mainz, Germany, 55116
Zentrum für Diabetes und Gefäßerkrankungen
Münster, Germany, 48145
Diabetes Zentrum Neuwied
Neuwied, Germany, 56564
ikfe Studiencenter Potsdam GmbH
Potsdam, Germany, 14469 收起 <<
United States, Minnesota
... 展开 >>
Minneapolis Medical Research Foundation
Minneapolis, Minnesota, United States, 55404
United States, New York
Columbia University
New York, New York, United States, 10027
United States, North Carolina
Wake Forest University
Winston-Salem, North Carolina, United States, 27106
United States, Ohio
Case Western Reserve University
Cleveland, Ohio, United States, 44106
United States, Tennessee
Veterans Affairs
Memphis, Tennessee, United States, 38104
United States, Washington
University of Washington
Seattle, Washington, United States, 98195
Canada, Ontario
McMaster University
Hamilton, Ontario, Canada 收起 <<
Austria
... 展开 >> Medical University of Viemma
Recruiting
Vienna, Austria, 1090
Contact: Jeanette Strametz-Juranek, MD 0043140400 ext 4618 jeanette.strametz-juranek@meduniwien.ac.at
Contact: Alexandra Kautzky-Willer, MD 0140400 ext 4316 alexandra.kautzky-willer@meduniwien.ac.at
Principal Investigator: Jeanette Strametz-Juranek, MD
Principal Investigator: Alexandra Kautzky-Willer, MD
Sub-Investigator: Alia Sabri, MD
Sub-Investigator: Lana Kosi, MD 收起 <<
United States, Florida
... 展开 >>
University of Miami
Recruiting
Miami, Florida, United States
Contact: Gianluca Iacobellis, MD GIacobellis@med.miami.edu
Principal Investigator: Gianluca Iacobellis, MD
United States, Georgia
Grady Memorial Hospital
Recruiting
Atlanta, Georgia, United States, 30303
Contact: Guillermo E Umpierrez, MD 404-778-1665 geumpie@emory.edu
Contact: Francisco J Pasquel, MD 404 778 1697 fpasque@emory.edu
Principal Investigator: Guillermo Umpierrez, MD
Sub-Investigator: Francisco J Pasquel, MD
Sub-Investigator: Priya Vellanki, MD
Emory University Hospital
Recruiting
Atlanta, Georgia, United States, 30324
Contact: Francisco Pasquel, MD fpasque@emory.edu
Sub-Investigator: Francisco Pasquel, MD
Emory Universtiy Hospital at MIdtown
Recruiting
Atlanta, Georgia, United States
Contact: Francisco Pasquel, MD
Sub-Investigator: Rodolfo J Galindo, MD
United States, New York
State University of NY at Buffalo
Recruiting
New York, New York, United States
Contact: Ajay Chaudhuri, MD AChaudhuri@KaleidaHealth.Org
Principal Investigator: Ajay Chaudhuri, MD 收起 <<
United States, Delaware
... 展开 >>
Research Site
Recruiting
Wilmington, Delaware, United States
United States, District of Columbia
Research Site
Recruiting
Washington, District of Columbia, United States
Netherlands
Research Site
Recruiting
Utrecht, Netherlands
United Kingdom
Research Site
Recruiting
London, United Kingdom 收起 <<
Korea, Republic of
... 展开 >>
Severance Hospital, Department of Internal Medicine, Yonsei University College of Medicine
Seoul, Korea, Republic of, 120-752 收起 <<
United Kingdom
... 展开 >> University Hospitals of Leicester
Leicester, Leicestershire, United Kingdom
University Hospital Birmingham
Birmingham, West Midlands, United Kingdom 收起 <<
Terminated(MBX-102 did not mee... 展开 >>t the target efficacy profile of HbA1c change.) 收起 <<
-
United States, California
... 展开 >>
Providence Clinical Research
Burbank, California, United States, 91505
American Institute of Research
Los Angeles, California, United States, 90017
United States, Nevada
Nevada Alliance Against Diabetes
Las Vegas, Nevada, United States, 89101
United States, North Carolina
Piedmont Medical Research Associates
Winston-Salem, North Carolina, United States, 27103
United States, Texas
DGD Research, Inc.
San Antonio, Texas, United States, 78229
India
Kamineni Hospitals Pvt, Ltd.
Hyderabad, Andhra Pradesh, India, 50008
Bangalore Diabetes Centre
Bangalore, India
Diacon Hospital Diabetes & Research Centre
Bangalore, India
M. S. Ramaiah Memorial Hospital
Bangalore, India
St. John's Medical College & Hospital
Bangalore, India
Dr. V. Seshiah Diabetes Care & Research Institute
Chennai, India
Mediciti Hospital
Hyderabad, India
Medwin Hospital
Hyderabad, India
Diabetes Thyroid Hormone Research Institute Pvt. Ltd.
Indore, India
Fortis Hospital
Jaipur, India
Bharti Research Institute of Diabetes & Endocrinology
Karnal, India
Amrita Institute of Medical Sciences
Kochi, India
Diabetes Action Centre
Mumbai, India, 400067
BYL Nair Hospital
Mumbai, India
PD Hindhuja National Hospital
Mumbai, India
Gandhi Endocrinology & Diabetes Centre
Nagpur, India
All India Institute of Medical Sciences
New Delhi, India
Deenanath Mangeshkar Hospital & Research Centre
Pune, India
Diabetes Care & Research Centre
Pune, India
Health & Research Centre
Trivendrum, India
Christian Medical College
Vellore, India 收起 <<
United States, Washington
... 展开 >>
VA Puget Sound Health Care System (Seattle Campus)
Seattle, Washington, United States, 98108
VA Puget Sound Health Care System (American Lake Campus)
Tacoma, Washington, United States, 98493 收起 <<
Argentina
... 展开 >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Mar Del Plata, Argentina, B7600FZN
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Ramos Mejia, Argentina, B1704ETD
Brazil
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Porto Alegre, Brazil, 90035-170
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
São Paulo, Brazil, 01244-030
China
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Changzhou, China, 213003
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Harbin, China, 150086
Egypt
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Alexandria, Egypt
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Cairo, Egypt, 11562
India
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Jaipur, India, 302018
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Vishakhapatnam, India, 530002
Korea, Republic of
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Daegu, Korea, Republic of, 700-712
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Goyang-Si, Korea, Republic of, 410-719
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Kyunggi-Do, Korea, Republic of, 425-020
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Seoul, Korea, Republic of, 134-090
Spain
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Málaga, Spain, 29010
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
San Boi De Llobregat, Spain, 08830
Turkey
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Antalya, Turkey, 07070
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Istanbul, Turkey, 34865 收起 <<
Obesity
Overw... 展开 >>eight With Indications for Weight Loss 收起 <<
Phase 4
Completed
-
United States, North Carolina
... 展开 >>
Sticht Center on Aging, Wake Forest University Baptist Medical Center
Winston-Salem, North Carolina, United States, 27157 收起 <<
United States, Maryland
... 展开 >>
National Institutes of Health Clinical Center
Recruiting
Bethesda, Maryland, United States, 20892
Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov 收起 <<
Australia, Victoria
... 展开 >>
Alfred Hospital
Recruiting
Melbourne, Victoria, Australia, 3004
Contact: Melissa F Formosa, B Sci +61 9076 6518 m.formosa@alfred.org.au
Principal Investigator: Bronwyn A Kingwell, PhD 收起 <<
Oral Cavity Neoplasm
... 展开 >> Oropharyngeal Neoplasm
Stage 0 Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage 0 Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7
Stage I Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage I Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7
Stage II Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage II Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7 收起 <<
Phase 2
Recruiting
March 31, 2019
United States, Maryland
... 展开 >>
Johns Hopkins University/Sidney Kimmel Cancer Center
Recruiting
Baltimore, Maryland, United States, 21287
Contact: Wayne M. Koch 410-995-4906 wkoch@jhmi.edu
Principal Investigator: Wayne M. Koch
United States, Minnesota
University of Minnesota/Masonic Cancer Center
Recruiting
Minneapolis, Minnesota, United States, 55455
Contact: Frank G. Ondrey 612-625-3200 ondre002@umn.edu
Principal Investigator: Frank G. Ondrey
United States, New York
University of Rochester
Recruiting
Rochester, New York, United States, 14642
Contact: Shawn D. Newlands 585-273-1943 Shawn_Newlands@URMC.Rochester.edu
Principal Investigator: Shawn D. Newlands
United States, Wisconsin
University of Wisconsin Hospital and Clinics
Recruiting
Madison, Wisconsin, United States, 53792
Contact: Aaron M. Wieland 608-265-8207 wieland@surgery.wisc.edu
Principal Investigator: Aaron M. Wieland 收起 <<
United States, California
... 展开 >>
Los Angeles, California, United States
United States, Florida
Miami Gardens, Florida, United States
West Palm Beach, Florida, United States
United States, Michigan
Kalamazoo, Michigan, United States
United States, South Carolina
Greenville, South Carolina, United States
United States, Texas
Dallas, Texas, United States
San Antonio, Texas, United States
United States, Washington
Renton, Washington, United States 收起 <<
United States, Arizona
... 展开 >>
Goodyear, Arizona, United States
United States, California
Chula Vista, California, United States
Los Angeles, California, United States
United States, Florida
Bradenton, Florida, United States
Hialeah, Florida, United States
Pembroke Pines, Florida, United States
United States, Illinois
Chicago, Illinois, United States
United States, Montana
Butte, Montana, United States
United States, North Carolina
Greensboro, North Carolina, United States
United States, Ohio
Cincinnati, Ohio, United States
United States, South Carolina
Charleston, South Carolina, United States
United States, Texas
Austin, Texas, United States
San Antonio, Texas, United States
United States, Utah
Salt Lake City, Utah, United States 收起 <<
Terminated(DSPD focussing on S... 展开 >>tudy 301 to confirm clinical profile before proceeding.) 收起 <<
-
United States, Alabama
... 展开 >>
Huntsville, Alabama, United States, 35801
Huntsville, Alabama, United States, 35802
United States, California
San Diego, California, United States, 92128
San Francisco, California, United States, 94115
United States, Connecticut
Ridgefield, Connecticut, United States, 06877
United States, Florida
Fort Lauderdale, Florida, United States, 33308
Pembroke Pines, Florida, United States, 33026
United States, Mississippi
Port Gibson, Mississippi, United States, 39150
United States, Nevada
Las Vegas, Nevada, United States, 89119
United States, New Mexico
Albuquerque, New Mexico, United States, 87109
United States, Ohio
Kettering, Ohio, United States, 45429
United States, Pennsylvania
Fleetwood, Pennsylvania, United States, 19522
Harrisburg, Pennsylvania, United States, 17112
United States, South Carolina
Simpsonville, South Carolina, United States, 29681
United States, Texas
Daingerfield, Texas, United States, 75638
Dallas, Texas, United States, 75216
Plano, Texas, United States, 75093
San Antonio, Texas, United States, 78205 收起 <<
United States, Texas
... 展开 >>
The University of Texas Health Science Center at San Antonio
Recruiting
San Antonio, Texas, United States, 78229
Contact: Ralph A DeFronzo, MD 210-567-6691 defronzo@uthscsa.edu
Contact: Monica Palomo, BS 210-567-6710 palomom@uthscsa.edu
Principal Investigator: Ralph A DeFronzo, MD
Sub-Investigator: Eugenio Cersosimo, MD 收起 <<
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