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Oxytetracycline HCI/盐酸氧四环素 {[allProObj[0].p_purity_real_show]}

货号:A734976 同义名: 盐酸土霉素 / OTC; Oxycycin

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Oxytetracycline HCI/盐酸氧四环素 化学结构 CAS号:2058-46-0
Oxytetracycline HCI/盐酸氧四环素 化学结构
CAS号:2058-46-0
Oxytetracycline HCI/盐酸氧四环素 3D分子结构
CAS号:2058-46-0
Oxytetracycline HCI/盐酸氧四环素 化学结构 CAS号:2058-46-0
Oxytetracycline HCI/盐酸氧四环素 3D分子结构 CAS号:2058-46-0
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Oxytetracycline HCI/盐酸氧四环素 纯度/质量文件 产品仅供科研

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Oxytetracycline HCI/盐酸氧四环素 生物活性

描述 Oxytetracycline hydrochloride, a member of the tetracycline class of antibiotics, effectively inhibits both Gram-negative and Gram-positive bacteria. It functions as a protein synthesis inhibitor by preventing the binding of aminoacyl-tRNA to the mRNA-ribosome complex and also exhibits anti-HSV-1 (Herpes Simplex Virus-1) activity[1].[2].[3].

Oxytetracycline HCI/盐酸氧四环素 动物研究

Animal study The pharmacological impact of oxytetracycline varies across species. When administered at a therapeutic dose of 82.8 mg/kg of body weight to 1% body weight per day for 10 days, it influences various biological parameters differently among fish species. In Morone chrysops x M. saxatilis, it increases relative liver weight. In Ictalurus punctatus, it enhances the enzymatic activity of CYP3A4, whereas in Oreochromis niloticus, it increases protein expression of CYP3A4 but depletes hepatic CYP3A4[1].Regulatory limits for oxytetracycline residue include 100 μg/kg in muscle and milk, 200 μg/kg in eggs, 300 μg/kg in liver, and 600 μg/kg in kidney tissues. In aquaculture, oxytetracycline is typically administered via medicated feed at concentrations ranging from 35 to 75 mg active ingredient per kg of biomass per day for durations of 7 to 14 days[1].

Oxytetracycline HCI/盐酸氧四环素 参考文献

[1]Elia AC, et al. Transferability of oxytetracycline (OTC) from feed to carp muscle and evaluation of the antibiotic effects on antioxidant systems in liver and kidney. Fish Physiol Biochem. 2014 Aug;40(4):1055-68.

[2]Pickens LB, et al. Oxytetracycline biosynthesis. J Biol Chem. 2010 Sep 3;285(36):27509-15.

[3]Oguz Guvenmez, et al. A New Treatment Method for Herpes Simplex Virus Type 1-related Skin Lesions. Scientific & Academic. 2019; 8(1): 6-8.

Oxytetracycline HCI/盐酸氧四环素 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.01mL

0.40mL

0.20mL

10.06mL

2.01mL

1.01mL

20.13mL

4.03mL

2.01mL

Oxytetracycline HCI/盐酸氧四环素 技术信息

CAS号2058-46-0
分子式C22H25ClN2O9
分子量 496.89
SMILES Code O=C(C1=C(O)[C@@H](N(C)C)[C@@]([C@@H](O)[C@@]2([H])C(C(C3=C(O)C=CC=C3[C@]2(O)C)=O)=C4O)([H])[C@@]4(O)C1=O)N.[H]Cl
MDL No. MFCD00135815
别名 盐酸土霉素 ;OTC; Oxycycin; Terramycin; Stevacin; Oxytetracycline(hydrochloride)
运输蓝冰
InChI Key SVDOODSCHVSYEK-IFLJXUKPSA-N
Pubchem ID 54680782
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place, inert atmosphere, 2-8°C

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