Ingenol | (-)-Ingenol | 巨大戟二萜醇 | Plant Standard | PKC | TGF-beta/Smad

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Ingenol/巨大戟醇 {[allProObj[0].p_purity_real_show]}

货号：A689957 同义名： 巨大戟二萜醇 / (-)-Ingenol

Ingenol is a diterpenoid with unique architecture and has derivatives possessing important anticancer activity.

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There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type	HazMat fee for 500 gram (Estimated)
Excepted Quantity	USD 0.00
Limited Quantity	USD 15-60
Inaccessible (Haz class 6.1), Domestic	USD 80+
Inaccessible (Haz class 6.1), International	USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic	USD 100+
Accessible (Haz class 3, 4, 5 or 8), International	USD 200+

Ingenol/巨大戟醇化学结构
CAS号：30220-46-3

Ingenol/巨大戟醇 3D分子结构
CAS号：30220-46-3

规格	价格	会员价	库存	数量
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Ingenol/巨大戟醇纯度/质量文件产品仅供科研

货号：A689957 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: 更多 >

转化生长因子-β 亚型比较
PKC 亚型比较

产品名称	ALK1 ↓ ↑	ALK2 ↓ ↑	ALK3 ↓ ↑	ALK4 ↓ ↑	ALK6 ↓ ↑	Smad3 ↓ ↑	TGF-β ↓ ↑	TGFβRI/ALK5 ↓ ↑	TGFβRII ↓ ↑	纯度
LDN193189	++++ ALK1, IC50: 0.8 nM	++++ ALK2, IC50: 0.8 nM	+++ ALK3, IC50: 5.3 nM		+++ ALK6, IC50: 16.7 nM					99%+
LDN-212854	++++ ALK1, IC50: 2.4 nM	++++ ALK2, IC50: 1.3 nM	+ ALK3, IC50: 85.8 nM	+ ALK4, IC50: 2133 nM				+ ALK5, IC50: 9276 nM		99%+
ML347	++ ALK1, IC50: 46 nM	++ ALK2, IC50: 32 nM								98%
K02288	++++ ALK1, IC50: 1.8 nM	++++ ALK2, IC50: 1.1 nM	++ ALK3, IC50: 34.4 nM		+++ ALK6, IC50: 6.4 nM					99%+
LDN-193189 2HCl	++++ ALK1, IC50: 0.8 nM	++++ ALK2, IC50: 0.8 nM	+++ ALK3, IC50: 5.3 nM		+++ ALK6, IC50: 16.7 nM					99%
LDN-214117		++ ALK2, IC50: 24 nM								98%
DMH-1		+ ALK2, IC50: 107.9 nM								99%+
SB-505124				+ ALK4, IC50: 129 nM				++ ALK5, IC50: 47 nM		99%+
Vactosertib				+++ ALK4, IC50: 13 nM				+++ ALK5, IC50: 11 nM		99%+
Alantolactone						✔				98%
SIS3						✔				97%
Pirfenidone							✔			98%
Hesperetin							✔			97%
RepSox								++++ TGFβR1(ALK5), IC50: 4 nM		98%
GW788388								+++ ALK5, IC50: 18 nM		98%
LY364947								++ TGFβRI, IC50: 59 nM	+ TGFβRII, IC50: 0.4 μM	98%
SD-208								++ TGF-βRI (ALK5), IC50: 48 nM		99%
SB-525334								+++ TGFβR1(ALK5), IC50: 14.3 nM		99%+
LY2109761								++ TβRI, Ki: 38 nM	+ TβRII, Ki: 300 nM	99%+
Galunisertib								++ TβRI, IC50: 56 nM		98%
SB 431542								+ ALK5, IC50: 94 nM		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

产品名称	PKC ↓ ↑	PKCα ↓ ↑	PKCβ ↓ ↑	PKCγ ↓ ↑	PKCδ ↓ ↑	PKCε ↓ ↑	PKCζ ↓ ↑	PKCη ↓ ↑	PKCθ ↓ ↑	其他靶点	纯度
Daphnetin	+ PKC, IC50: 25.01 μM									EGFR,PKA	95%
Dequalinium Chloride											99%+
Quercetin	✔									Sirtuin,Src	97%
Myricetrin		✔									96%
Go 6983		+++ PKCα, IC50: 7 nM	+++ PKCβ, IC50: 7 nM	+++ PKCγ, IC50: 6 nM	+++ PKCδ, IC50: 10 nM		++ PKCζ, IC50: 60 nM				99%+
Go6976	+++ PKC, IC50: 7.9 nM	++++ PKCα, IC50: 2.3 nM	+++ PKCβ1, IC50: 6.2 nM							FLT3	99%+
Bisindolylmaleimide I		+++ PKCα, IC50: 20 nM	+++ PKCβ2, IC50: 16 nM PKCβ1, IC50: 17 nM	+++ PKCγ, IC50: 20 nM							99%+
Lawsone methyl ether			✔								99%
Sotrastaurin		++++ PKCα, Ki: 0.95 nM	++++ PKCβ1, Ki: 0.64 nM		++++ PKCδ, Ki: 2.1 nM	++++ PKCε, Ki: 3.2 nM		++++ PKCη, Ki: 1.8 nM	++++ PKCθ, Ki: 0.22 nM		99%+
Enzastaurin		++ PKCα, IC50: 39 nM	+++ PKCβ, IC50: 6 nM	+ PKCγ, IC50: 83 nM		+ PKCε, IC50: 110 nM					98%
Midostaurin		++ PKCα, IC50: 22 nM	++ PKCβ2, IC50: 31 nM PKCβ1, IC50: 30 nM	++ PKCγ, IC50: 24 nM	+ PKCδ, IC50: 330 nM	+ PKCε, IC50: 1.25 μM		+ PKCη, IC50: 160 nM			99%
Ro 31-8220 mesylate		++++ PKCα, IC50: 5 nM	+++ PKCβ2, IC50: 14 nM PKCβ1, IC50: 24 nM	++ PKCγ, IC50: 27 nM		++ PKCε, IC50: 24 nM					99%+
Staurosporine		++++ PKCα, IC50: 2 nM		++++ PKCγ, IC50: 5 nM	+++ PKCδ, IC50: 20 nM	++ PKCε, IC50: 73 nM		++++ PKCη, IC50: 4 nM			99%+
Ruboxistaurin HCl		+ PKCα, IC50: 0.36 μM	++++ PKCβ2, IC50: 5.9 nM PKCβ1, IC50: 4.7 nM	+ PKCγ, IC50: 0.3 μM	+ PKCδ, IC50: 0.25 μM			++ PKCη, IC50: 0.052 μM			99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Ingenol/巨大戟醇生物活性

描述	Ingenol is an extremely weak PKC (protein kinase C) activator and has been found to induce apoptosis and act as an anticancer agent.

Ingenol/巨大戟醇临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01541553	Actinic Keratosis	Phase 3	Completed	-	-
NCT02531295	HIV Human Imm... 展开 >>unodeficiency Virus 收起 <<	Phase 1	Recruiting	November 2020	United States, Utah ... 展开 >> University of Utah Recruiting Salt Lake City, Utah, United States, 84132 Contact: Adam M Spivak, MD 801-585-2031 adam.spivak@hsc.utah.edu Contact: Zachary Mitchell (801) 587-7467 zachary.mitchell@hsc.utah.edu Principal Investigator: Sulggi A Lee, MD PhD Principal Investigator: Adam M Spivak, MD Sub-Investigator: Steven G Deeks, MD 收起 <<
NCT01541553	-		Completed	-	-

Ingenol/巨大戟醇参考文献

[1]Armstrong S, Ganote CE. Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia. Cardiovasc Res. 1994 Nov;28(11):1700-6.

[2]Hasler CM, Acs G, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.

Ingenol/巨大戟醇实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

2.87mL

0.57mL

0.29mL

14.35mL

2.87mL

1.44mL

28.70mL

5.74mL

2.87mL

Ingenol/巨大戟醇技术信息

CAS号	30220-46-3
分子式	C₂₀H₂₈O₅
分子量	348.43
SMILES Code	O=C1[C@]2([H])[C@@]3([H])[C@@](C3(C)C)([H])C[C@@H](C)[C@@](C=C(C)[C@@H]4O)1[C@]4(O)[C@H](O)C(CO)=C2
MDL No.	MFCD27980538

别名	巨大戟二萜醇 ;(-)-Ingenol
运输	蓝冰

存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry, store in freezer, under -20°C

溶解方案

动物实验：请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议现用现配，当天使用；以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

方案一

方案二

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01541553	Actinic Keratosis	Phase 3	Completed	-	-
NCT02531295	HIV Human Imm... 展开 >>unodeficiency Virus 收起 <<	Phase 1	Recruiting	November 2020	United States, Utah ... 展开 >> University of Utah Recruiting Salt Lake City, Utah, United States, 84132 Contact: Adam M Spivak, MD 801-585-2031 adam.spivak@hsc.utah.edu Contact: Zachary Mitchell (801) 587-7467 zachary.mitchell@hsc.utah.edu Principal Investigator: Sulggi A Lee, MD PhD Principal Investigator: Adam M Spivak, MD Sub-Investigator: Steven G Deeks, MD 收起 <<
NCT01541553	-		Completed	-	-
NCT03508856	Actinic Keratosis ... 展开 >> Photo-aged Skin 收起 <<	Not Applicable	Completed	-	-
NCT02385318	Actinic Keratosis	Phase 3	Completed	-	-
NCT02459795	Actinic Keratosis	Phase 3	Completed	-	-
NCT02362152	-		Completed	-	Netherlands ... 展开 >> Lievensberg Ziekenhuis Bergen op Zoom, Netherlands, 4624 收起 <<
NCT00916006	-		Completed	-	-
NCT00916006	Actinic Keratosis	Phase 3	Completed	-	United States, California ... 展开 >> Dermatology Research Associates Los Angeles, California, United States, 90045 Dermatology Specialists Inc Oceanside, California, United States, 92056 Skin Surgery Medical Group Inc. San Diego, California, United States, 92117 Conant Medical Group San Francisco, California, United States, 94114 United States, Florida University of Miami, Skin Research Camp Miami, Florida, United States, 33136 United States, Georgia Atlanta Dermatology, Vein & Research Center, LLC Alpharetta, Georgia, United States, 30022 Medaphase Inc Newnan, Georgia, United States, 30263 United States, Illinois Glazer Dermatology Buffalo Grove, Illinois, United States, 60089 United States, Indiana Dawes Fretein Clinical Research Group, LLC Indianapolis, Indiana, United States, 46256 United States, Kentucky Pedia Research LLC Owensboro, Kentucky, United States, 42301 United States, Michigan Hamzavi Dermatology Fort Gratiot, Michigan, United States, 48059 United States, Minnesota Minnesota Clinical Study Center Fridley, Minnesota, United States, 55432 United States, North Carolina Wake Research Associates Raleigh, North Carolina, United States, 27612 United States, Tennessee Dermatology Research Associates Nashville, Tennessee, United States, 37203 United States, Texas J & S Studies, Inc. College Station, Texas, United States, 77845 Dermatology Associates of Tyler Tyler, Texas, United States, 75703 Center for Clinical Studies Webster, Texas, United States, 77598 United States, Utah Dermatology Research Center, Inc. Salt Lake City, Utah, United States, 84124 United States, Virginia Virginia Clinical Research, Inc Norfolk, Virginia, United States, 23507 Australia, New South Wales Southderm Pty Ltd Kogarah, New South Wales, Australia, 2217 St George Dematology and Skin Cancer Centre Kogarah, New South Wales, Australia, 2217 收起 <<
NCT00917306	Actinic Keratosis	Phase 3	Completed	-	United States, Florida ... 展开 >> Park Avenue Dermatology Orange Park, Florida, United States, 32073 United States, Georgia Medaphase Inc Newnan, Georgia, United States, 30263 Gwinnett Clinical Research Centre Snellville, Georgia, United States, 30078-3250 United States, Michigan Michigan Center for Research Corp Clinton Twp, Michigan, United States, 48038 Henry Ford Health Systems Detroit, Michigan, United States, 48202 United States, New York Dermatology Associates of Rochester Rochester, New York, United States, 14623 United States, Oregon Oregon Health and Science University Portland, Oregon, United States, 97239-4501 United States, Tennessee Dermatology Research Associates Nashville, Tennessee, United States, 37203 Australia, South Australia Dematology on Ward Adelaide, South Australia, Australia, 5006 Australia, Victoria Dermatology Institute of Victoria Melbourne, Victoria, Australia, 3141 Australia, Western Australia St John of God Dermatology Subiaco, Western Australia, Australia, 6008 收起 <<
NCT02281682	Keratosis, Actinic	Phase 4	Active, not recruiting	December 2018	Netherlands ... 展开 >> Maastricht UMC Maastricht, Limburg, Netherlands, 6202 AZ 收起 <<
NCT01387711	Actinic Keratosis	Phase 1	Completed	-	Germany ... 展开 >> Universitätsmedizin Göttingen, Georg-August-Universität Göttingen, Germany, D-37075 收起 <<
NCT01449513	-		Completed	-	-
NCT02723721	Lentigo Maligna	Phase 2	Recruiting	November 2020	France ... 展开 >> AP-HP Hopital Avicenne Not yet recruiting Bobigny, France, 93000 Contact: Liliane LAROCHE, PU-PH AP-HP Hôpital Ambroise Paré Not yet recruiting boulogne Billancourt, France Contact: Philippe SAIAG, PH Hôpital du Morvan Not yet recruiting Brest, France Contact: Laurent MISERY, PU-PH CHRU de Lille Recruiting Lille, France Contact: Laurent MORTIER, PU-PH CHU de Nantes Not yet recruiting Nantes, France Contact: Brigitte DRENO, PU-PH CHU de Nice Recruiting Nice, France, 06000 Principal Investigator: Henri MONTAUDIE, PH Hôpital Pontchaillou Not yet recruiting Rennes, France Contact: Alain DUPUY, PU-PH CHU de Saint Etienne Recruiting Saint Etienne, France Contact: Frederic CAMBAZARD, PU-PH 收起 <<
NCT03546166	Carcinoma	Phase 2	Not yet recruiting	June 2020	-
NCT01214577	Photo-damage	Phase 2	Completed	-	Australia, Queensland ... 展开 >> The Skin Centre Benowa, Queensland, Australia, 4217 Specialist Connect Woolloongabba, Queensland, Australia, 4102 收起 <<
NCT00742391	-		Completed	-	-
NCT02446223	Actinic Keratosis	Phase 4	Completed	-	United States, California ... 展开 >> Cosmetic Laser Dermatology San Diego, California, United States, 92121 收起 <<
NCT00915551	Actinic Keratosis	Phase 3	Completed	-	-
NCT01449513	Actinic Keratosis	Phase 1	Completed	-	Germany ... 展开 >> Charité - Universitätsmedizin Berlin Berlin, Germany, 10117 收起 <<
NCT00915551	-		Completed	-	-
NCT00850811	Actinic Keratosis	Phase 1	Completed	-	United States, New Jersey ... 展开 >> TKL Research, Inc. Paramus, New Jersey, United States, 07652 收起 <<
NCT00942604	Actinic Keratoses	Phase 3	Completed	-	United States, Arizona ... 展开 >> Burke Pharmaceutical Research Hot Springs, Arizona, United States, 71913 United States, California Skin Surgery Medical Group Inc. San Diego, California, United States, 92117 United States, Georgia Atlanta Dermatology, Vein & Research Center, LLC Alpharetta, Georgia, United States, 30022 United States, Illinois Altman Dermatology Associates Arlington Heights, Illinois, United States, 60005 Glazer Dermatology Buffalo Grove, Illinois, United States, 60089 United States, Indiana Deaconess Clinic Downtown Evansville, Indiana, United States, 47713 Dawes Fretzin Clinical Research Group, LLC Indianapolis, Indiana, United States, 46256 United States, Nebraska Skin Specialists, PC Omaha, Nebraska, United States, 68144 United States, Nevada Karl G. Heine Dermatology Henderson, Nevada, United States, 89002 United States, Ohio Group Health Associates Cincinnati, Ohio, United States, 45220 United States, Texas DermResearch, Inc. Austin, Texas, United States, 78759 Suzanne Bruce and Associates, PA, The Center for Skin Research Houston, Texas, United States, 77056 Dermatology Clinical Research Center of San Antonio San Antonio, Texas, United States, 78229 Dermatology Associates of Tyler Tyler, Texas, United States, 75703 United States, Utah Dermatology Research Center, Inc. Salt Lake City, Utah, United States, 84124 United States, Virginia The Education and Research Foundation Lynchburg, Virginia, United States, 24501 Virginia Clinical Research, Inc Norfolk, Virginia, United States, 23507 收起 <<
NCT00742391	Actinic Keratoses	Phase 3	Completed	-	United States, Arizona ... 展开 >> Omni Dermatology Research Mesa, Arizona, United States, 85206 United States, Colorado Colorado Medical Research Center Denver, Colorado, United States, 80210 United States, Florida Advanced Dermatology and Cosmetic Research Kissimmee, Florida, United States, 34741 Park Avenue Dermatology Orange Park, Florida, United States, 32073 Advanced Dermatology & Cosmetic Surgery Ormond Beach, Florida, United States, 32174 United States, Georgia Medaphase Inc Newnan, Georgia, United States, 30263 Gwinnett Clinical Research Centre Snellville, Georgia, United States, 30078-3250 United States, Indiana Dermatology Center of Indiana/Indiana Clinical Trials Center Plainfield, Indiana, United States, 46168 United States, Michigan Henry Ford Health Systems Detroit, Michigan, United States, 48202 United States, New Jersey Karen S. Harkaway, MD. LLC South Delran, New Jersey, United States, 08075 United States, New Mexico Academic Dermatology Associates Albuquerque, New Mexico, United States, 87106 United States, New York Dermatology Associates of Rochester Rochester, New York, United States, 14623 United States, Ohio University Hospitals Case Medical Center Cleveland, Ohio, United States, 44121 United States, Oregon Oregon Medical Research Portland, Oregon, United States, 97223 Oregon Health and Science University Portland, Oregon, United States, 97239-4501 United States, Tennessee Dermatology East Germantown, Tennessee, United States, 38138 Rivergate Dermatology and Skin Care Center Goodlettsville, Tennessee, United States, 37072 United States, Texas J & S Studies, Inc. College Station, Texas, United States, 77845 Australia, Queensland The Skin Centre Benowa, Queensland, Australia, 4217 Australia, Western Australia Burswood Dermatology Victoria Park, Western Australia, Australia, 6100 收起 <<
NCT01214564	Seborrheic Keratosis	Phase 2	Completed	-	Australia, New South Wales ... 展开 >> Southderm Pty Ltd Kogarah, New South Wales, Australia, 2217 Australia, Queensland Specialist Connect Woolloongabba, Queensland, Australia, 4102 收起 <<
NCT00942604	-		Completed	-	-
NCT01302925	Healthy Actin... 展开 >>ic Keratosis 收起 <<	Phase 1	Completed	-	United States, New Jersey ... 展开 >> TKL Research Paramus, New Jersey, United States 收起 <<
NCT01325688	Superficial Basal Cell Carcino... 展开 >>ma 收起 <<	Phase 2	Completed	-	Australia, New South Wales ... 展开 >> Southderm Pty Ltd Kogarah, New South Wales, Australia, 2217 St George Dermatology Kogarah, New South Wales, Australia, 2217 Australia, Queensland The Skin Centre Benowa, Queensland, Australia, 4217 Specialist Connect Woolloongabba, Queensland, Australia, 4102 Australia, Victoria Dermatology Institute of Victoria South Yarra, Victoria, Australia, 3141 Australia, Western Australia St John of God Dermatology Subiaco, Western Australia, Australia, 6008 Burswood Dermatology Victoria Park, Western Australia, Australia, 6100 收起 <<
NCT01820260	Actinic Keratosis	Phase 1 Phase 2	Completed	-	United States, Indiana ... 展开 >> Laser & Skin Surgery Center of Inidana Carmel, Indiana, United States, 46032 收起 <<
NCT01998984	Actinic Keratosis	Phase 2	Completed	-	United States, New York ... 展开 >> Long Island Skin Cancer and Dermatologic Surgery Smithtown, New York, United States 收起 <<
NCT01892137	Actinic Keratosis	Phase 1	Completed	-	Australia, New South Wales ... 展开 >> Southderm Pty Ltd Kogarah, New South Wales, Australia, 2217 Melanoma Institute Australia north Sydney, New South Wales, Australia, 2060 Australia, Queensland The Skin Centre Benowa, Queensland, Australia, 4217 South East Dermatology Centre Carina Heights, Queensland, Australia, 4152 Australia, Western Australia St John of God Dermatology Subiaco, Western Australia, Australia, 6008 Burswood Dermatology Victoria Park, Western Australia, Australia, 6100 Germany Klinik für Dermatologie & Allergologie Klinikum Augsburg Süd Augsburg, Germany, 86179 Collegium Medicum Berlin GmbH Berlin, Germany, 10117 Medizinisches Zentrum Bonn Friedensplatz Bonn, Germany, 42275 Hautarztpraxis Prof. Dr. med. C. Termeer Stuttgart, Germany, 70499 收起 <<
NCT01998984	-		Completed	-	-
NCT00850681	Actinic Keratosis	Phase 1	Completed	-	United States, New Jersey ... 展开 >> TKL Research, Inc. Paramus, New Jersey, United States, 07652 收起 <<
NCT02090465	-		Unknown	April 2014	Germany ... 展开 >> Universitätsklinikum Heidelberg/Klinische Sozialmedizin Recruiting Heidelberg, Germany, D-69115 Contact: Thomas L. Diepgen, Prof.Dr.med. +49 6221568751 thomas.diepgen@med.uni-heidelberg.de Principal Investigator: Thomas L Diepgen, Prof.Dr.med. 收起 <<
NCT02361216	Actinic Keratosis	Phase 3	Completed	-	United States, Indiana ... 展开 >> Laser & Skin Surgery Center of Indiana Carmel, Indiana, United States, 46032 收起 <<
NCT02361216	-		Completed	-	-
NCT02124239	Actinic Keratosis	Phase 1	Completed	-	United States, New Mexico ... 展开 >> Academic Dermatology Associate Albuquerque, New Mexico, United States, 47106 收起 <<
NCT02654769	Actinic Keratosis	Phase 3	Completed	-	United States, California ... 展开 >> Center for Dermatology Clinical Research, Inc Fremont, California, United States, 94538 SD Sports Medicine & Family Health Center San Diego, California, United States, 92120 United States, Florida The Center for Clinical and Cosmetic Research Aventura, Florida, United States, 33180 Savin Medical Group Research Center Miami Lakes, Florida, United States, 33014 Tory P. Sullivan, M.D., P.A. North Miami Beach, Florida, United States, 33162 Moore Clinical Research, Inc. Tampa, Florida, United States, 33609 United States, Idaho Northwest Clinical Trials, Inc. Boise, Idaho, United States, 83704 United States, Illinois Altman Dermatology Associates Arlington Heights, Illinois, United States, 60005 Christie Clinic, LLC Champaign, Illinois, United States, 61820 United States, Indiana Shideler Clinical Research Center Carmel, Indiana, United States, 46032 Dawes Fretzin Clinical Research Group, LLC Indianapolis, Indiana, United States, 46256 The Indiana Clinical Trials Center Plainfield, Indiana, United States, 46168 United States, Nevada Bettencourt Skin Center Henderson, Nevada, United States, 89074 United States, New York Union Square Dermatology New York, New York, United States, 10003 United States, North Carolina Dermatology Consulting Services High Point, North Carolina, United States, 27262 PMG Research of Winston-Salem, LLC Winston-Salem, North Carolina, United States, 27103 United States, Rhode Island Omega Medical Research, 400 Bald Hill Road, Warwick, RI 02886 Warwick, Rhode Island, United States, 02886 United States, South Carolina Greenville Dermatology, LLC Greenville, South Carolina, United States, 29607 United States, Tennessee Dermatology Associates of Knoxville, PC Knoxville, Tennessee, United States, 37917 United States, Texas DermResearch, Inc.Austin Austin, Texas, United States, 78759 The Center for Skin Research Houston, Texas, United States, 77056 United States, Virginia Virginia Clinical Research Norfolk, Virginia, United States, 23507 收起 <<
NCT02406014	Actinic Keratosis (AK)	Phase 4	Completed	-	Germany ... 展开 >> Gemain, Weber & Craninic Schweinfurt, Germany, 97421 收起 <<
NCT03200912	ACTINIC KERATOSIS	Phase 3	Completed	-	-
NCT01735942	Actinic Keratosis	Early Phase 1	Withdrawn	May 2016	-
NCT02242747	Actinic Keratosis	Not Applicable	Completed	-	Brazil ... 展开 >> Hospital das Clínicas of the University of São Paulo Medical School (HCFMUSP) Sao Paulo, Brazil, 05403000 收起 <<
NCT01803477	Actinic Keratosis	Phase 1 Phase 2	Completed	-	Australia, Queensland ... 展开 >> Dermatology Department Woolloongabba, Queensland, Australia, 4102 Specialist Connect Woolloongabba, Queensland, Australia, 4102 收起 <<
NCT03569345	Carcinoma, Basal Cell	Phase 1 Phase 2	Completed	-	Denmark ... 展开 >> Department of Dermtology, Bispebjerg University Hospital, Copenhagen, Denmark Copenhagen, Denmark, 2400 收起 <<
NCT00852137	-		Completed	-	-
NCT01600014	Actinic Keratosis	Phase 3	Completed	-	Australia ... 展开 >> St John of God Dermatology Subiaco, Australia, 6008 Canada, Alberta Stratica Medical Edmonton, Alberta, Canada, T5K 1X3 Canada, British Columbia Skin Care Centre Vancouver, British Columbia, Canada, V5Z 4E8 Canada, Manitoba Dermadvances Research Winnipeg, Manitoba, Canada, R3C 1R4 Canada, New Brunswick Durondel C.P. Inc./Dermatology Clinic Moncton, New Brunswick, Canada, E1C 8X3 Canada, Ontario UltraNova Skincare Barrie, Ontario, Canada, L4M 6L2 SKiN Centre for Dermatology Peterborough, Ontario, Canada, K9J 1Z2 Windsor Clinical Research Inc. Windsor, Ontario, Canada, N8W 5L7 Canada, Quebec Innovaderm Research Inc. Montreal, Quebec, Canada, H2K 4L5 Canada Centre de Recherche Dermatologique Quebec, Canada, G1V 4X7 France CHU de Nantes Nantes, Loire-Atlantique 6, France, 44000 Germany Universitätsklinikum Tübingen Tübingen, Germany, 72076 United Kingdom Central Manchester University Hosptial Manchester, Greater Manchester, United Kingdom, M13 9WL 收起 <<
NCT02411851	Actinic Keratoses	Phase 1	Completed	-	United States, New York ... 展开 >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 收起 <<
NCT02990221	Actinic Keratosis	Phase 4	Active, not recruiting	July 2018	Italy ... 展开 >> Second University of Naples Naples, Italy, 80131 收起 <<
NCT02421471	-		Completed	-	Korea, Republic of ... 展开 >> Department of Dermatology, Korea University Anam Hospital Seoul, Korea, Republic of 收起 <<
NCT01600014	-		Completed	-	-
NCT02473848	Actinic Keratosis	Phase 3	Terminated(Lack of enrolment)	-	Switzerland ... 展开 >> Dermatology Department University Hospital Zürich Zürich, Switzerland, 8091 收起 <<
NCT01703078	Actinic Keratosis	Phase 1	Completed	-	Australia, Queensland ... 展开 >> Dermatology Department Woolloongabba, Queensland, Australia, 4102 收起 <<
NCT00852137	Actinic Keratosis	Phase 2	Completed	-	United States, Texas ... 展开 >> DermResearch, Inc. Austin, Texas, United States, 78759 收起 <<
NCT02716714	-		Completed	-	-
NCT02354391	Actinic Keratosis	Phase 2	Active, not recruiting	December 2018	-
NCT01787383	Actinic Keratosis	Phase 3	Completed	-	Italy ... 展开 >> Clinica Dermatologica dell'Università di Modena e Reggio Emilia Modena, Italy, 41124 收起 <<
NCT02716714	Actinic Keratosis	Phase 4	Completed	-	Korea, Republic of ... 展开 >> Korea University Ansan Hospital Ansan-si, Gyeonggi-do, Korea, Republic of, 15355 收起 <<
NCT03115476	Actinic Keratoses ... 展开 >> Squamous Cell Carcinoma 收起 <<	Phase 3	Terminated(Study halted premat... 展开 >>urely and will not resume; participants are no longer being examined.) 收起 <<	-	-
NCT02748902	Verruca Vulgaris ... 展开 >> Common Warts 收起 <<	Phase 1	Completed	-	United States, California ... 展开 >> Therapeutics Clinical Research San Diego, California, United States, 92123 收起 <<
NCT02251652	-		Completed	-	-
NCT02251652	Actinic Keratoses	Phase 4	Completed	-	United States, New York ... 展开 >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 11370 收起 <<
NCT01926496	Actinic Keratosis (AK)	Phase 4	Active, not recruiting	October 2019	-
NCT02594436	-		Completed	-	Greece ... 展开 >> Office Based Physician Athens, Peristeri, Greece, 12134 收起 <<
NCT02866695	Actinic Keratosis	Phase 4	Completed	-	United States, California ... 展开 >> UCSF Dermatology San Francisco, California, United States, 94115 收起 <<
NCT01787383	-		Completed	-	-
NCT01836367	Actinic Keratosis	Phase 1	Completed	-	United States, New York ... 展开 >> Icahn School of Medicine at Mount Sinai New York, New York, United States, 10029 收起 <<
NCT03452566	Actinic Cheilitis	Phase 1 Phase 2	Not yet recruiting	April 2020	-

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