货号：A100956同义名：
人参皂甙 Rg1
/ Panaxoside Rg1; Panaxoside A
Ginsenoside Rg1, a natural product isolated and purified from the roots of Panax ginseng C. A. Mey., is a functional ligand of glucocorticoid receptor(GR) that can boost the production of insulin receptors, stimulates the creation of new blood vessels and wound healing, relaxes and widens blood vessels and lowers blood pressure, and is a potent phytoestrogen with estrogen-like activity.
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has anti-inflammatory actions. In vitro, ginsenoside Rg1 functioned to HK-2 cells in a dose-dependent manner, and the 150 μM dose exhibited the most protective functions. Ginsenoside Rg1 protects HK-2 cells against LPS-induced inflammation and apoptosis[3]. Moreover, ginsenoside Rg1 alleviates CS-induced pulmonary EMT in both COPD rats and HBE cells[4]. In vivo, Ginsenoside Rg1 treatment (10 mg/mL) lameliorated depression-like behaviors and reduced chronic unpredictable mild stress exposure-Induced microglial activation and inflammatory cytokine expression within the ventral medial prefrontal cortex[5].
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