GBR 12783 2HCl
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货号：A1251037
同义名：
GBR 12783 dihydrochloride
GBR 12783 2HCl 化学结构
GBR 12783 2HCl 3D分子结构
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GBR 12783 2HCl 纯度/质量文件 产品仅供科研
货号：A1251037
标准纯度：
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GBR 12783 2HCl 质控信息
Penfluridol
+
Dopamine receptor, Ki: 1.6 μM
98%
Ansofaxine HCl
++
Dopamine receptor, IC50: 491 nM
99%
Tetrahydroberberine
+
98+%
Prochlorperazine Maleate
✔
98% (HPLC)
Olanzapine
✔
99+%
Trifluoperazine
++++
Dopamine D2 receptor, IC50: 1.1 nM
98%
Ropinirole HCl
++
99%
Lurasidone
++++
98%
Levosulpiride
✔
99+%
Pridopidine
✔
95%
Metoclopramide
✔
✔
99+%
Molindone HCl
✔
99%
Sulpiride
✔
99+%
Perospirone
++++
99%
Perospirone HCl
++++
99%
Phenothiazine
✔
98%
Pimozide
+
Dopamine D1 receptor, Ki: 6600 nM
+++
Dopamine D2 receptor, Ki: 3.0 nM
++++
Dopamine D3 receptor, Ki: 0.83 nM
98%
Rotundine
++
D1 receptor, IC50: 166 nM
+
D2 receptor, IC50: 1.47 μM
+
D3 receptor, IC50: 3.25 μM
98%
Domperidone
✔
99+%
ONC206
✔
99%
Pimethixene maleate
++
Dopamine D1 Receptor, pKi: 6.37
+++
Dopamine D2 Receptor, pKi: 8.19
++
Dopamine D4.4 Receptor, pKi: 7.54
97%
Loxapine succinate
++
D2 receptor (Human), Ki: 62 nM
D1 receptor (human), Ki: 26 nM
++
D2 receptor (human), Ki: 24 nM
D2 receptor (bovine), Ki: 26 nM
+++
D4 receptor (human), Ki: 7.5 nM
98%
Chlorprothixene
+++
+++
+++
+++
99%
SCH-23390 HCl
++++
D1 dopamine receptor, Ki: 0.2 nM
++++
D5 dopamine receptor, Ki: 0.3 nM
98%
MPP+ iodide
✔
97%
σ1 Receptor antagonist-1
+
97%
Benztropine mesylate
++
98%
Azaperone
✔
98%
Ziprasidone HCl
✔
98+%
Paliperidone
✔
98%
Alizapride HCl
✔
99+%
Amisulpride
✔
98%
Quetiapine hemifumarate
✔
Adrenergic Receptor
98%
Clozapine N-oxide
✔
99%
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
GBR 12783 2HCl 生物活性
描述
GBR 12783 dihydrochloride is a distinct, powerful, and selective inhibitor of dopamine reuptake, effectively blocking [3H]dopamine absorption in synaptosomes from rat and mouse striatum with IC50 values of 1.8 nM and 1.2 nM, respectively. It has been shown to enhance memory function and stimulate the release of acetylcholine in the hippocampus of rats[1] [2]
GBR 12783 2HCl 实验方案
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1mg
5mg
10mg
1 mM
5 mM
10 mM
2.06mL
0.41mL
0.21mL
10.30mL
2.06mL
1.03mL
20.60mL
4.12mL
2.06mL
GBR 12783 2HCl 技术信息
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