G15 is a high-affinity and selective GPER receptor antagonist with Ki value of 20nM.
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HazMat fee for 500 gram (Estimated)
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Accessible (Haz class 3, 4, 5 or 8), International
G15 is a high-affinity and selective GPER receptor antagonist with Ki value of 20nM[1]. It exhibits low-affinity cross-reactivity with the canonical estrogen receptor (ER) ERα, such that it mediates limited ER-dependent transcriptional activity at doses greater than 1 µM[2]. G-15 antagonizes the anti-depressive effects of estrogen in vivo at dose of 10mg/kg, i.p.[1].
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