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Furaltadone HCI/盐酸呋喃它酮 {[allProObj[0].p_purity_real_show]}

货号:A211792 同义名: 盐酸呋喃他酮 / Altafur hydrochloride; Furaltadone HCl

Furaltadone HCl is a veterinary product used for the treatment and control of salmonella infection of poultry.

Furaltadone HCI/盐酸呋喃它酮 化学结构 CAS号:3759-92-0
Furaltadone HCI/盐酸呋喃它酮 化学结构
CAS号:3759-92-0
Furaltadone HCI/盐酸呋喃它酮 3D分子结构
CAS号:3759-92-0
Furaltadone HCI/盐酸呋喃它酮 化学结构 CAS号:3759-92-0
Furaltadone HCI/盐酸呋喃它酮 3D分子结构 CAS号:3759-92-0
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Furaltadone HCI/盐酸呋喃它酮 纯度/质量文件 产品仅供科研

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Furaltadone HCI/盐酸呋喃它酮 生物活性

描述 Furaltadone hydrochloride, a nitrofuran drug, is inhibitory and bactericidal in vitro for staphylococci. Furaltadone inhibited the degranulation of mast cells stimulated by antigen (IC50, ~ 3.9 μM), and also suppressed the production of tumor necrosis factor (TNF)-α and interleukin (IL)-4 in a concentration dependent manner. In addition, furaltadone inhibited allergic responses in an acute allergy animal model, PCA(passive cutaneous anaphylaxis) [3]. Furazolidone is probably the most effective drug available for treatment of avian vibrionic hepatitis[4].

Furaltadone HCI/盐酸呋喃它酮 参考文献

[1]Zolla L, Timperio AM. Involvement of active oxygen species in protein and oligonucleotide degradation induced by nitrofurans. Biochem Cell Biol. 2005 Apr;83(2):166-75.

[2]Eleazer TH, Bierer BW. Furaltadone hydrochloride in treatment of avian vibrionic hepatitis and chronic respiratory disease complex in chickens. Poult Sci. 1967 Jul;46(4):819-22.

[3]Nam ST, Kim HW, Kim HS, Park YH, Lee D, Lee MB, Min KY, Kim YM, Choi WS. Furaltadone suppresses IgE-mediated allergic response through the inhibition of Lyn/Syk pathway in mast cells. Eur J Pharmacol. 2018 Jun 5;828:119-125

[4]Eleazer TH, Bierer BW. Furaltadone hydrochloride in treatment of avian vibrionic hepatitis and chronic respiratory disease complex in chickens. Poult Sci. 1967 Jul;46(4):819-22

Furaltadone HCI/盐酸呋喃它酮 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.77mL

0.55mL

0.28mL

13.86mL

2.77mL

1.39mL

27.72mL

5.54mL

2.77mL

Furaltadone HCI/盐酸呋喃它酮 技术信息

CAS号3759-92-0
分子式C13H17ClN4O6
分子量 360.75
SMILES Code O=C1OC(CN2CCOCC2)CN1/N=C/C3=CC=C([N+]([O-])=O)O3.Cl
MDL No. MFCD00058201
别名 盐酸呋喃他酮 ;Altafur hydrochloride; Furaltadone HCl; Furaltadone(hydrochloride)
运输蓝冰
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Keep in dark place, inert atmosphere, 2-8°C

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