Flunarizine
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货号：A721246
Flunarizine 化学结构
CAS号：52468-60-7
Flunarizine 3D分子结构
CAS号：52468-60-7
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Flunarizine 纯度/质量文件 产品仅供科研
货号：A721246
标准纯度：
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Flunarizine 质控信息
- Calcium Channel 亚型比较
- 多巴胺受体 亚型比较
- 钠通道 亚型比较
| CDC25B-IN-2 |
✔
|
|
|
Akt
|
99%+ |
| Clevidipine |
|
✔
|
|
|
97% |
| Verapamil HCl |
|
✔
|
|
|
99% |
| Amlodipine |
|
✔
|
|
|
99% |
| Amlodipine maleate |
|
✔
|
|
|
98% |
| (+)-cis-Diltiazem HCl |
|
✔
|
|
|
99% |
| Zegocractin |
|
++
Orai1/STIM1-mediated Ca2+ currents, IC50: 120 nM
|
|
|
99%+ |
| Tanshinone IIA sulfonate sodium |
|
✔
|
|
|
98% |
| Ulixacaltamide |
|
++
hCaV3.2, IC50: 110 nM
hCaV3.1, IC50: 50 nM
|
|
|
99%+ |
| Dronedarone HCl |
|
✔
|
|
|
95% |
| Nitrendipine |
|
+
Calcium channel, IC50: 95 nM
|
|
|
98% |
| Efonidipine HCl monoethanolate |
|
✔
|
|
|
98% |
| Cinnarizine |
|
✔
|
|
|
98% |
| SEA0400 |
|
++
|
|
ROS,ERK,p38 MAPK
|
99%+ |
| Fasudil HCl |
|
✔
|
|
Rho,PKA
|
98% |
| ML-9 |
|
✔
|
|
MLCK,Akt
|
99%+ |
| Flunarizine 2HCl |
|
+
Calcium channel, Ki: 68 nM
|
|
|
95% |
| Lomerizine 2HCl |
|
✔
|
|
|
98% |
| Efonidipine |
|
✔
|
|
|
98% |
| Levamlodipine |
|
✔
|
|
|
98% |
| Nisoldipine |
|
++
L-type Cav1.2, IC50: 10 nM
|
|
|
97% |
| Isradipine |
|
✔
|
|
|
98% |
| Lacidipine |
|
✔
|
|
|
98% |
| Lercanidipine |
|
✔
|
|
|
99% |
| Loureirin B |
|
✔
|
|
Potassium Channel
|
99%+ |
| Tetracaine HCl |
|
✔
|
|
|
98% |
| Manidipine |
|
+++
Calcium channel, IC50: 2.6 nM
|
|
|
99% |
| Manidipine Dihydrochlorid |
|
+++
Calcium channel, IC50: 2.6 nM
|
|
|
98% |
| Nicardipine |
|
✔
|
|
|
99% |
| Wilforgine |
|
✔
|
|
|
98+% |
| Econazole |
|
✔
|
|
|
99%+ |
| Ginsenoside Rd |
|
✔
|
|
NF-κB
|
98% |
| Fendiline HCl |
|
✔
|
|
|
98+% |
| Mesaconitine |
|
✔
|
|
|
98% |
| Tetrandrine |
|
✔
|
|
|
95% |
| Nifedipine |
|
✔
|
|
|
95% |
| Nilvadipine |
|
++++
Calcium channel, IC50: 0.03 nM
|
|
|
98% |
| Barnidipine |
|
++++
[3H]nitrendipine, Ki: 0.21 nM
|
|
|
95+% |
| Azelnidipine |
|
✔
|
|
|
97% |
| Levetiracetam |
|
✔
|
|
|
98% |
| Nimodipine |
|
✔
|
|
|
95% |
| Benidipine HCl |
|
✔
|
|
|
98% |
| Pinaverium bromide |
|
✔
|
|
|
98% |
| Pranidipine |
|
✔
|
|
|
99% |
| NP118809 |
|
+
L-type calcium channel, IC50: 12.2 μM
N-type Ca2+ channel, IC50: 0.11 μM
|
|
|
98% |
| Amlodipine Besylate |
|
+++
Calcium channel, IC50: 1.9 nM
|
|
|
97% |
| Cilnidipine |
|
✔
|
|
|
99% |
| Cinepazide Maleate |
|
✔
|
|
|
99% (HPLC) |
| Terfenadine |
|
✔
|
|
|
98% |
| YM-58483 |
|
✔
|
|
|
99%+ |
| Ranolazine |
|
✔
|
|
|
98% |
| Praeruptorin A |
|
✔
|
|
p38 MAPK,Akt
|
98% |
| Ranolazine 2HCl |
|
✔
|
|
|
98% |
| Felodipine |
|
++++
L-type calcium channel, IC50: 0.15 nM
|
|
|
98% |
| PD173212 |
|
+++
N-type Ca2+ channel, IC50: 36 nM
|
|
|
98% |
| Levamlodipine besylate |
|
✔
|
|
|
97% |
| Carboxyamidotriazole Orotate |
|
✔
|
|
|
98% |
| IGS-1.76 |
|
✔
|
|
|
98+% |
| WH-4-023 |
|
++++
|
++++
|
|
99%+ |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
| Penfluridol |
+
Dopamine receptor, Ki: 1.6 μM
|
|
|
|
|
|
|
|
98% |
| Ansofaxine HCl |
++
Dopamine receptor, IC50: 491 nM
|
|
|
|
|
|
|
|
99% |
| Tetrahydroberberine |
|
+
|
|
|
|
|
|
|
98+% |
| Prochlorperazine Maleate |
|
✔
|
|
|
|
|
|
|
98% (HPLC) |
| Olanzapine |
|
✔
|
|
|
|
|
|
|
99+% |
| Trifluoperazine |
|
++++
Dopamine D2 receptor, IC50: 1.1 nM
|
|
|
|
|
|
|
98% |
| Ropinirole HCl |
|
++
|
|
|
|
|
|
|
99% |
| Lurasidone |
|
++++
|
|
|
|
|
|
|
98% |
| Levosulpiride |
|
✔
|
|
|
|
|
|
|
99+% |
| Pridopidine |
|
✔
|
|
|
|
|
|
|
95% |
| Metoclopramide |
|
✔
|
|
|
|
|
✔
|
|
99+% |
| Molindone HCl |
|
✔
|
|
|
|
|
|
|
99% |
| Sulpiride |
|
✔
|
|
|
|
|
|
|
99+% |
| Perospirone |
|
++++
|
|
|
|
|
|
|
99% |
| Perospirone HCl |
|
++++
|
|
|
|
|
|
|
99% |
| Phenothiazine |
|
✔
|
|
|
|
|
|
|
98% |
| Pimozide |
+
Dopamine D1 receptor, Ki: 6600 nM
|
+++
Dopamine D2 receptor, Ki: 3.0 nM
|
++++
Dopamine D3 receptor, Ki: 0.83 nM
|
|
|
|
|
|
98% |
| Rotundine |
++
D1 receptor, IC50: 166 nM
|
+
D2 receptor, IC50: 1.47 μM
|
+
D3 receptor, IC50: 3.25 μM
|
|
|
|
|
|
98% |
| Domperidone |
|
✔
|
|
|
|
|
|
|
99+% |
| ONC206 |
|
✔
|
|
|
|
|
|
|
99% |
| Pimethixene maleate |
++
Dopamine D1 Receptor, pKi: 6.37
|
+++
Dopamine D2 Receptor, pKi: 8.19
|
|
++
Dopamine D4.4 Receptor, pKi: 7.54
|
|
|
|
|
97% |
| Loxapine succinate |
++
D1 receptor (human), Ki: 26 nM
D2 receptor (Human), Ki: 62 nM
|
++
D2 receptor (human), Ki: 24 nM
D2 receptor (bovine), Ki: 26 nM
|
|
+++
D4 receptor (human), Ki: 7.5 nM
|
|
|
|
|
98% |
| Chlorprothixene |
+++
|
+++
|
+++
|
|
+++
|
|
|
|
99% |
| SCH-23390 HCl |
++++
D1 dopamine receptor, Ki: 0.2 nM
|
|
|
|
++++
D5 dopamine receptor, Ki: 0.3 nM
|
|
|
|
98% |
| MPP+ iodide |
|
|
|
|
|
✔
|
|
|
97% |
| σ1 Receptor antagonist-1 |
|
|
|
|
|
+
|
|
|
97% |
| Benztropine mesylate |
|
|
|
|
|
++
|
|
|
98% |
| Azaperone |
|
|
|
|
|
|
✔
|
|
98% |
| Ziprasidone HCl |
|
|
|
|
|
|
✔
|
|
98+% |
| Paliperidone |
|
|
|
|
|
|
✔
|
|
98% |
| Alizapride HCl |
|
|
|
|
|
|
✔
|
|
99+% |
| Amisulpride |
|
|
|
|
|
|
✔
|
|
98% |
| Quetiapine hemifumarate |
|
|
|
|
|
|
✔
|
Adrenergic Receptor
|
98% |
| Clozapine N-oxide |
|
|
|
|
|
|
✔
|
|
99% |
|
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
Flunarizine 实验方案
| 计算器 |
|
| 存储液制备 |
 |
1mg |
5mg |
10mg |
|
1 mM
5 mM
10 mM
|
2.47mL
0.49mL
0.25mL
|
12.36mL
2.47mL
1.24mL
|
24.72mL
4.94mL
2.47mL
|
Flunarizine 技术信息
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