Febantel is widely used anthelmintic drug active against a range of gastrointestinal parasites in animals[3]. The febantel tablet decreased the hookworm egg count by 99.9% and the whipworm egg count by 100%. The controlled test efficacies of febantel tablets against Ancylostoma caninum, Ancylostoma braziliense, and Trichuris vulpis were, 98.2%, 100% and 99.7%, respectively[4]. Febantel was rapidly cleared from the circulation and highly metabolized. The efficacy against Ascaridia was 100% for the faecal egg count reduction (FECR) as well as for the worm reduction in all treated pigeons. After two treatments with febantel against Capillaria in heavily infected pigeons the FECR amounted to 96.7% and worm reduction was 95%. In order to effectively remove both parasites from the host, repeated treatments with febantel at a short interval could be the treatment of choice[5]. Febantel alone, effectively eliminated Giardia trophozoites at 160 and 80 mg/kg mongolian gerbils. Febantel combined with pyrantel embonate effectively eliminated Giardia trophozoites at 160, 80 and 40 mg/kg. However, febantel is more effective in elimination of Giardia infections when combined with pyrantel embonate compared to the agents used alone[6].
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