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Deferoxamine/去铁胺 {[allProObj[0].p_purity_real_show]}

货号：A698741 同义名： Deferoxamine B; Deferrioxamine

Deferoxamine is a medication that binds iron and aluminium. It has been previously reported to induce hypoxia and hypoxia-inducible factor-1α (HIF-1α) expression.

Deferoxamine/去铁胺化学结构
CAS号：70-51-9

Deferoxamine/去铁胺 3D分子结构
CAS号：70-51-9

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Deferoxamine/去铁胺纯度/质量文件产品仅供科研

货号：A698741 标准纯度： {[allProObj[0].p_purity_real_show]} 产品说明书

批次查询：批次纯度: COA SDS NMR HPLC CNMR LC-MS

全球学术期刊中引用的产品: 更多 >

Akt 亚型比较
自噬亚型比较
HIF 亚型比较

产品名称	Akt ↓ ↑	Akt1 ↓ ↑	Akt2 ↓ ↑	Akt3 ↓ ↑	其他靶点	纯度
Honokiol	✔				MEK	98%
PF-04691502	++++ P-Akt (T308), IC50: 7.5 nM P-Akt (S473), IC50: 3.8 nM					98+%
PHT-427	+ Akt, Ki: 2.7 μM					99%+
Deguelin	✔				PI3K	99%+
TIC10 isomer	✔				ERK	98+%
Perifosine	+ Akt, IC50: 4.7 μM					98%
Miltefosine	✔				PKC,PI3K	98%
Triciribine	+ Akt, IC50: 130 nM					99%+
Uprosertib		+ Akt1, IC50: 180 nM	+ Akt2, IC50: 328 nM	++ Akt3, IC50: 38 nM		99%+
Afuresertib		++++ Akt1, Ki: 0.08 nM	++++ Akt2, Ki: 2 nM	++++ Akt3, Ki: 2.6 nM		99%+
Miransertib		++++ Akt1, IC50: 5 nM	++++ Akt2, IC50: 4.5 nM	++ Akt3, IC50: 16 nM		98+%
GSK-690693		++++ Akt1, IC50: 2 nM	+++ Akt2, IC50: 13 nM	+++ Akt3, IC50: 9 nM		99%+
AT7867		++ Akt1, IC50: 32 nM	++ Akt2, IC50: 17 nM	++ Akt3, IC50: 47 nM	PKA	99%+
AKT inhibitor VIII		++ Akt1, IC50: 58 nM	+ Akt2, IC50: 210 nM	+ Akt3, IC50: 2119 nM		97%
MK-2206 2HCl		+++ Akt1, IC50: 8 nM	+++ Akt2, IC50: 12 nM	+ Akt3, IC50: 65 nM		99%+
Ipatasertib		++++ Akt1, IC50: 5 nM	++ Akt2, IC50: 18 nM	+++ Akt3, IC50: 8 nM		99%+
AT13148		++ Akt1, IC50: 38 nM	+ Akt2, IC50: 402 nM	++ Akt3, IC50: 50 nM	PKA	95%
Capivasertib		++++ Akt1, IC50: 3 nM	+++ Akt2, IC50: 8 nM	+++ Akt3, IC50: 8 nM		99%+
A-674563 HCl		+++ Akt1, Ki: 11 nM			PKA	99%
CCT128930			+++ Akt2, IC50: 6 nM		PKA	95%
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

产品名称	Autophagy ↓ ↑	其他靶点	纯度
SBI-0206965	+++ ULK2, IC50: 711 nM ULK1, IC50: 108 nM		95%
Hydroxychloroquine sulfate	✔		99%
Valproic acid sodium	✔	HDAC	97%
PFK-015	++ PFKFB3, IC50: 207 nM		99%+
MRT68921 HCl	++++ ULK2, IC50: 1.1 nM ULK1, IC50: 2.9 nM		99%+
ROC-325	✔		99%+
Autophinib	+++ Autophagy, IC50: 40 nM		99%
Lys05	✔		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

产品名称	HIF ↓ ↑	HIF1 ↓ ↑	PHD1 ↓ ↑	PHD2 ↓ ↑	PHD3 ↓ ↑	其他靶点	纯度
KC7F2	+ HIF-1α, IC50: 20 μM	+ HIF-1α, IC50: 20 μM					98%
Lificiguat	✔						99%+
BAY 87-2243	✔						99%+
PX-478·2HCl	✔						98%+
2-Methoxyestradiol	✔						98%
CAY10585	++ HIF, IC50: 4.4 μM					BCRP	97%
DMOG			✔				98%
FG 2216				++ PHD2, IC50: 3.9 μM			99%+
MK-8617			++++ PHD1, IC50: 1 nM	++++ PHD2, IC50: 1 nM	++++ PHD3, IC50: 14 nM		99%+
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。

Deferoxamine/去铁胺生物活性

描述	Deferoxamine is a medication that binds iron and aluminium. It has been previously reported to induce hypoxia and hypoxia-inducible factor-1α (HIF-1α) expression.

Deferoxamine/去铁胺临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT00502788	Hepatitis C T... 展开 >>halassemia 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Children's Hospital and Research Center at Oakland Oakland, California, United States, 94609 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital Philadelphia Philadelphia, Pennsylvania, United States, 19104 Canada, Ontario Toronto General Hospital, Universty Health Network Toronto, Ontario, Canada, M5G 2C4 United Kingdom University College London London, United Kingdom, WC1E 6HX 收起 <<
NCT00447694	Beta-thalassemia ... 展开 >> Iron Overload 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Childrens Hospital of Los Angeles Los Angeles, California, United States, 90027 Children's Hospital and Research Center at Oakland Oakland, California, United States, 94609 United States, Illinois Children's Memorial Hospital Chicago, Illinois, United States, 60614 收起 <<
NCT01441375	-		Completed	-	United States, Louisiana ... 展开 >> Tulane University New Orleans, Louisiana, United States, 70112 United States, Tennessee Universit of Tennessee Memphis, Tennessee, United States, 38163 收起 <<

Deferoxamine/去铁胺参考文献

[1]Mu S, Guo S, et al. Effects of deferoxamine on the osteogenic differentiation of human periodontal ligament cells. Mol Med Rep. 2017 Dec;16(6):9579-9586.

[2]Yu J, Yuan Q, et al. Effects of Deferoxamine Mesylate on Hematoma and Perihematoma Edema after Traumatic Intracerebral Hemorrhage. J Neurotrauma. 2017 Oct 1;34(19):2753-2759.

Deferoxamine/去铁胺实验方案

计算器

存储液制备

1mg

5mg

10mg

1 mM

5 mM

10 mM

1.78mL

0.36mL

0.18mL

8.92mL

1.78mL

0.89mL

17.84mL

3.57mL

1.78mL

Deferoxamine/去铁胺技术信息

CAS号	70-51-9
分子式	C₂₅H₄₈N₆O₈
分子量	560.68
SMILES Code	O=C(N(CCCCCN)O)CCC(NCCCCCN(C(CCC(NCCCCCN(C(C)=O)O)=O)=O)O)=O
MDL No.	MFCD00242585

别名	Deferoxamine B; Deferrioxamine; Deferriferrioxamine B
运输	蓝冰

存储条件	In solvent -20°C:3-6个月-80°C:12个月 Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C

临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT00502788	Hepatitis C T... 展开 >>halassemia 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Children's Hospital and Research Center at Oakland Oakland, California, United States, 94609 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital Philadelphia Philadelphia, Pennsylvania, United States, 19104 Canada, Ontario Toronto General Hospital, Universty Health Network Toronto, Ontario, Canada, M5G 2C4 United Kingdom University College London London, United Kingdom, WC1E 6HX 收起 <<
NCT00447694	Beta-thalassemia ... 展开 >> Iron Overload 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Childrens Hospital of Los Angeles Los Angeles, California, United States, 90027 Children's Hospital and Research Center at Oakland Oakland, California, United States, 94609 United States, Illinois Children's Memorial Hospital Chicago, Illinois, United States, 60614 收起 <<
NCT01441375	-		Completed	-	United States, Louisiana ... 展开 >> Tulane University New Orleans, Louisiana, United States, 70112 United States, Tennessee Universit of Tennessee Memphis, Tennessee, United States, 38163 收起 <<
NCT01838291	-		Completed	-	Cyprus ... 展开 >> Thalassemia Center of North Cyprus Turkish Republic (KKTC) Nicosia, Cyprus Egypt Hematology Unit, El-Shatby Children Hospital, Alexandria University Alexandria, Egypt Hematology Unit, Assiut University Hospital Assiut, Egypt Ain Shams University Cairo, Egypt Hematology Unit, Mansoura University Children Hospital Mansoura, Egypt Tanta University Hospital Tanta, Egypt Hematology/Oncology Unit ; Zagazig University Children Hospital Zagazig, Egypt Zagazig University; Thalassemia Association Zagazig, Egypt Oman Department of Child Health, College of Medicine and Health Sciences, Sultan Qaboos University Hospital Muscat, Oman Saudi Arabia King Abdulaziz University Hospital (KAAUH) Jeddah, Saudi Arabia Maternity and Children's Hospital Maddinah, Saudi Arabia Turkey Çukurova Üniversitesi Tip Fakültesi, Çocuk Hematolojie Bilim Dali Adana, Turkey Akdeniz Üniversitesi Hastanesi, Çocuk Sağliği, Hematolojie Kliniği Antalya, Turkey Ïstanbul Üniversitesi Tip. Fak. Hastanesi, Çocuk Sağliği, Hematolojie Kliniği Istanbul, Turkey 收起 <<
NCT02443545	Iron Overload ... 展开 >> Sickle Cell Disease Other Anemias 收起 <<	Phase 4	Enrolling by invitation	March 2022	United States, California ... 展开 >> UCSF Benioff Children's Hospital Oakland Oakland, California, United States, 94609 United States, Michigan University of Michigan Comprehensive Cancer Center Ann Arbor, Michigan, United States, 48109 Children's Hospital of Michigan Detroit, Michigan, United States, 48201 United States, Pennsylvania The Children's Hospital of Philadephia Philadelphia, Pennsylvania, United States, 19104-4399 United States, South Carolina Medical University of South Carolina Charleston, South Carolina, United States, 29425 Canada, Ontario Hospital for Sick Kids Toronto, Ontario, Canada Egypt Zagazig University Alexandria, Egypt Ain Shams University Cairo, Egypt Cairo University Cairo, Egypt Pediatric Hospital of Cairo University Cairo, Egypt Saudi Arabia Asser Central Hospital Abha, Saudi Arabia United Kingdom Barts and The London London, United Kingdom Evelina Children's Hospital London, United Kingdom 收起 <<
NCT00171171	Beta-Thalassemia ... 展开 >> Hemosiderosis 收起 <<	Phase 3	Completed	-	Egypt ... 展开 >> Novartis Investigative Site Cairo, Egypt Lebanon Ali Taher Beirut, Lebanon, Riad El Solh 1107 2020 Oman Novartis Investigative Site Muscat, Oman Saudi Arabia Novartis Investigative Site Riyadh, Saudi Arabia Syrian Arab Republic Novartis Investigative Site Damascus, Syrian Arab Republic 收起 <<
NCT01825512	Chronic Iron Overload	Phase 3	Completed	-	Albania ... 展开 >> Hospital 'Ihsan Çabej' Lushnjë, Albania Qendra Spitalore Universitare "Nene Tereza" Tirane Tirana, Albania Cyprus Department of Medical and Public health Services of the Ministry of Health Nicosia, Cyprus Egypt Alexandria University Hospital - Faculty of Medicine Alexandria, Egypt Cairo University Faculty of Medicine Cairo, Egypt Zagazig University Hospitals Zagazig, Egypt Greece National And Kapodistrian University of Athens Athens, Greece Italy Centro di Thalassemia, Ospedale Civile di Lentini Lentini, SR, Italy Università di Bari - Facoltà di Medicina Bari, Italy ASL Cagliari Ospedale Regionale per le Microcitemie Cagliari, Italy Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione Garibaldi Catania, Italy Presidio Ospedaliero "Annunziata", Centro di Studi della Microcitemia Cosenza, Italy A.O.Universitaria Meyer Firenze, Italy Clinica Pediatrica Policlinico di Modena Modena, Italy Azienda Ospedaliera di Rilievo Nazionale "Antonio Cardarelli" Napoli, Italy Azienda Ospedaliera di Padova Padova, Italy Ospedale Di Cristina Palermo, Italy Ospedali Riuniti Villa Sofia - Cervello Palermo, Italy Clinica Pediatrica Università - ASL 1 D.H per Talassemia Sassari, Italy Tunisia Centre National de Greffe de Moelle Osseuse Tunis Tunis, Tunisia United Kingdom Barts Health NHS Trust London, United Kingdom Queen's Hospital Romford, United Kingdom 收起 <<
NCT01795794	CDA Type I	Phase 4	Unknown	December 2013	-
NCT00578344	Sickle Cell Disease ... 展开 >> Hemoglobin SC 收起 <<	Not Applicable	Terminated(Terminated due to n... 展开 >>o new subject enrollment during the last 3 year period.) 收起 <<	-	United States, Texas ... 展开 >> Methodist Hospital Houston, Texas, United States, 77030 Texas Children's Hospital Houston, Texas, United States, 77030 收起 <<
NCT00171210	Transfusional Iron Overload in... 展开 >> β-thalassemia 收起 <<	Phase 3	Completed	-	-
NCT00000623	-		Completed	-	United States, California ... 展开 >> Children's Hospital Oakland Oakland, California, United States, 94609 United States, Massachusetts Children's Hospital Boston, Massachusetts, United States, 02115 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Canada, Ontario Toronto General Hospital Toronto, Ontario, Canada, M5G 2C4 收起 <<
NCT01935661	-		Enrolling by invitation	December 31, 2018	Israel ... 展开 >> Haemek Medical Center Afula, Israel 收起 <<
NCT00171210	-		Completed	-	-
NCT02233504	High Risk MDS or AML Patients	Early Phase 1	Active, not recruiting	October 2019	United States, Pennsylvania ... 展开 >> Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 收起 <<
NCT00110266	Myelodysplastic Syndrome ... 展开 >> Iron Overload 收起 <<	Phase 2	Completed	-	-
NCT01905774	-		Completed	-	Israel ... 展开 >> Ha'Emek Medical Center Afula, Israel, 18101 收起 <<
NCT01956799	-		Active, not recruiting	December 2018	Italy ... 展开 >> Ematologia, AO SS. Antonio e Biagio Alessandria, AL, Italy, 15121 Clinica di Ematologia, AOU Ospedale di Torrette Ancona, AN, Italy, 60020 Ematologia con trapianto, AOU Policlinico di Bari Bari, BA, Italy, 70124 Istituto di Ematologia e Oncologia Medica, Policlinico S.Orsola Bologna, BO, Italy, 40138 Ematologia, Spedali Civili Brescia, BS, Italy, 25123 Struttura complessa di Ematologia, ASO S.Croce e Carle Cuneo, CN, Italy, 12100 Cattedra di Ematologia Policlino Careggi Firenze, FI, Italy, 50134 Clinica Ematologica, Università di Genova Genova, GE, Italy, 16132 U.O. Clinica Medicina Interna, IRCCS San Martino IST Genova, GE, Italy, 16132 UO Ematologia e CTMO, Ospedale Civile G. da Saliceto Piacenza, PC, Italy, 29121 Ematologia, Università di Padova Padova, PD, Italy, 35128 Struttura Cattedra di Ematologia e CTMO, AOU di Parma Parma, PR, Italy, 43100 Ematologia e Centro Trapianti, Centro di Riferimento Oncologico della Basilicata Rionero in Vulture, PZ, Italy, 85028 Medicina Interna II Divisione di Ematologia, Ospedale S. Luigi Gonzaga Orbassano, TO, Italy, 10043 Ematologia 2, AOU Città della Salute e della Scienza Torino, TO, Italy, 10126 S.C.D.U. Ematologia e Terapie cellulari, Ospedale Mauriziano Torino, TO, Italy, 10128 UOC Ematologia, Ospedale S.Eugenio Roma, Italy, 00144 Policlinico A.Gemelli Roma, Italy, 00168 UOC Ematologia, AO S. Giovanni Addolorata Roma, Italy, 00184 Ematologia, AO S. Andrea Roma, Italy, 00189 收起 <<
NCT01033747	Liver Iron Overload	Phase 2 Phase 3	Completed	-	Italy ... 展开 >> Novartis Investigative Site Cagliari, Italy Novartis Investigative Site Genova, Italy Novartis Investigative Site Milan, Italy Novartis Investigative Site Torino, Italy 收起 <<
NCT00004982	Iron Overload ... 展开 >> Thalassemia 收起 <<	Phase 1	Completed	-	United States, New York ... 展开 >> Cornell University Medical College New York, New York, United States, 10021 收起 <<
NCT01752153	Immune Abnormalities	Phase 1	Completed	-	Iran, Islamic Republic of ... 展开 >> Department of Immunology, School of Medicine, Shiraz University of Medical Sciences Shiraz, Fars, Iran, Islamic Republic of 收起 <<
NCT02065492	Thalassemia	Phase 2 Phase 3	Completed	-	Pakistan ... 展开 >> Aga Khan University Hospital Karachi, Sindh, Pakistan, 74800 收起 <<
NCT00749515	Transfusion-dependent Hemachro... 展开 >>matosis Thalassemia Major Sickle Cell Disease 收起 <<	Phase 4	Completed	-	United States, Massachusetts ... 展开 >> Children's Hospital Boston Boston, Massachusetts, United States, 02115 收起 <<
NCT00733811	Beta-Thalassemia ... 展开 >> Thalassemia Major 收起 <<	Phase 4	Completed	-	Italy ... 展开 >> Ao V. Cervello Palermo, Italy 收起 <<
NCT00999349	Beta-thalassemia Major ... 展开 >> Iron Overload 收起 <<	Phase 2 Phase 3	Unknown	-	Iran, Islamic Republic of ... 展开 >> Isfahan University of Medical Sciences Isfahan, Iran, Islamic Republic of, 81744-176 收起 <<
NCT01459718	Transfusion-dependent β-thalas... 展开 >>semia Patients Cardiac Iron Overload 收起 <<	Phase 2	Completed	-	Greece ... 展开 >> Novartis Investigative Site Athens, GR, Greece, 115 27 Novartis Investigative Site Athens, GR, Greece, GR-115 27 Novartis Investigative Site Athens, Greece, GR Novartis Investigative Site Patras, Greece, 26500 收起 <<
NCT01033747	-		Completed	-	-
NCT01996683	Beta-thalassemia ... 展开 >> Serum Ferritin Iron Chelation Therapy 收起 <<	Not Applicable	Unknown	November 2015	Egypt ... 展开 >> Pediatric Hematology clinic, Ain Shams University Not yet recruiting Cairo, Egypt Principal Investigator: Mohsen S Elalfy, professor Sub-Investigator: Amira A Adly, Assist. prof. Sub-Investigator: Yasmine I Elhenawy, lecturer 收起 <<
NCT01365104	Stroke Proble... 展开 >>m of Aging 收起 <<	Early Phase 1	Completed	-	United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 收起 <<
NCT00293098	-		-	-	United States, Pennsylvania ... 展开 >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 收起 <<
NCT01511848	Beta-thalassemia Major ... 展开 >> Sickle Cell Disease Iron Hemosiderosis 收起 <<	Phase 2 Phase 3	Unknown	February 2013	Egypt ... 展开 >> Pediatric Hematology clinic, Ain Shams University Not yet recruiting Cairo, Egypt 收起 <<
NCT01090323	Sickle Cell Disease	Phase 2	Completed	-	-
NCT02041299	Iron Overload ... 展开 >> Sickle Cell Disease Other Anemias 收起 <<	Phase 4	Recruiting	September 2019	-
NCT01090323	-		Completed	-	-
NCT00000595	Anemia (Iron-Loading) ... 展开 >> Beta-Thalassemia Hematologic Diseases Hemoglobinopathies Thalassemia Iron Overload Hemochromatosis 收起 <<	Phase 2	Completed	-	-
NCT00115349	Cardiovascular Diseases ... 展开 >> Heart Diseases Beta-Thalassemia 收起 <<	Phase 2	Terminated(due to low enrollme... 展开 >>nt) 收起 <<	-	United States, California ... 展开 >> Children's Hospital of Los Angeles Los Angeles, California, United States, 90027 Children's Hospital Oakland, California, United States, 94609 United States, Illinois Children's Memorial Hospital Chicago, Illinois, United States, 60614-3394 United States, Massachusetts Children's Hospital Boston, Massachusetts, United States, 02115 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104-4399 收起 <<
NCT00061763	Beta-thalassemia ... 展开 >> Myelodysplastic Syndromes Fanconi Syndrome Anemia, Diamond-Blackfan Anemia, Aplastic 收起 <<	Phase 2	Completed	-	United States, California ... 展开 >> Children's Hospital Oakland Oakland, California, United States, 94609 Stanford Hospital Stanford, California, United States, 94305-5208 United States, Illinois Northwest Medical Specialists Arlington Heights, Illinois, United States, 60004 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104-4318 收起 <<
NCT00103753	Beta-Thalassemia	Phase 4	Unknown	-	Italy ... 展开 >> Ospedale Microcitemico, Via Jenner Cagliari, Sardinia, Italy, 09121 收起 <<
NCT00350662	Hemochromatosis	Phase 3	Completed	-	Egypt ... 展开 >> Pediatric Hospital, Cairo University Cairo, Egypt Turkey EGE University Medical School Bornova, Izmir, Izmir, Turkey, 35100 收起 <<
NCT00115349	-		Terminated(due to low enrollme... 展开 >>nt) 收起 <<	-	-
NCT00001203	-		Completed	-	United States, Maryland ... 展开 >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 收起 <<
NCT00349453	Hemochromatosis	Phase 2	Completed	-	Switzerland ... 展开 >> Cantonal Hospital, Children's Clinic Aarau, Aargau, Switzerland, 5001 Cantonal Hospital Aarau, Aargau, Switzerland, 5001 Cantonal Hospital Graubünden Chur, Graubünden, Switzerland, 7000 Private practice Arzo, Ticino, Switzerland, 6864 Private practice Lugano, Ticino, Switzerland, 6900 Regional Hospital Lugano, Ticino, Switzerland, 6900 Private practice Riva San Vitale, Ticino, Switzerland, 6826 Private children's practice Brig, Wallis, Switzerland, 3900 Private practice Oerlikon, Zurich, Switzerland, 8050 Private children's practice Bern, Switzerland, 3014 Children's Hospital of Eastern Switzerland St. Gallen, Switzerland, 9006 University Children's Hospital Zurich, Switzerland, 8032 University Hospital Zurich, Switzerland, 8091 收起 <<
NCT00105495	Thalassemia Major ... 展开 >> Hemosiderosis 收起 <<	Phase 4	Completed	-	Greece ... 展开 >> 1st Department of Pediatrics, Athens University, Aghia Sophia Children's Hospital Athens, Greece, 11527 Aghia Sophia Children's Hospital Athens, Greece, 11527 Italy Ospedale Regionale Microcitemie, Dipartimento di Scienze Cagliari, Sardegna, Italy, 09100 Dipartimento di Scienze e Dell' Adolescenza, University of Turin Turin, Italy, 10126 收起 <<
NCT00901199	Thalassemia I... 展开 >>ron Overload 收起 <<	Phase 4	Completed	-	United States, California ... 展开 >> CHRCO Oakland, California, United States, 94609 收起 <<
NCT00600938	Transfusional Iron Overload ... 展开 >> Transfusional Hemosiderosis 收起 <<	Phase 2	Completed	-	Canada, Ontario ... 展开 >> Novartis Investigative Site Toronto, Ontario, Canada, M5G 1X8 China, Guangxi Novartis Investigative Site Nanning, Guangxi, China, 530021 Cyprus Novartis Investigative Site Limassol, Cyprus, 3304 Egypt Novartis Investigative Site Cairo, Egypt Novartis Investigative Site Mansoura, Egypt Italy Novartis Investigative Site Cagliari, CA, Italy, 09121 Novartis Investigative Site Genova, GE, Italy, 16128 Lebanon Novartis Investigative Site Hazmiyeh, Lebanon Taiwan Novartis Investigative Site Taipei, Taiwan, 10002 Thailand Novartis Investigative Site Bangkok, Thailand, 10330 Novartis Investigative Site Bangkok, Thailand, 10700 Turkey Novartis Investigative Site Adana, Turkey, 01330 Novartis Investigative Site Ankara, Turkey, 06100 Novartis Investigative Site Antalya, Turkey, 07070 Novartis Investigative Site Istanbul, Turkey, 34093 Novartis Investigative Site Izmir, Turkey, 35040 United Arab Emirates Novartis Investigative Site Dubai, United Arab Emirates, 9115 United Kingdom Novartis Investigative Site Leeds, West Yorkshire, United Kingdom, LS9 7TF Novartis Investigative Site Leeds, United Kingdom, LS9 7TF Novartis Investigative Site London, United Kingdom, N19 5NF Novartis Investigative Site London, United Kingdom, NW1 2PJ 收起 <<
NCT00110617	Sickle Cell Disease ... 展开 >> Iron Overload Hemolytic Anemia 收起 <<	Phase 2	Completed	-	-
NCT00800761	Iron Overload ... 展开 >> Cardiomyopathy 收起 <<	Phase 4	Completed	-	Italy ... 展开 >> Adult Talassemic Center, Ospedale Microcitemico Cagliari, Sardinia, Italy, 09121 收起 <<
NCT00067080	Anemia, Sickle Cell	Phase 2	Completed	-	-
NCT01369719	Thalassemia I... 展开 >>ron Overload Transfusion Related Complications 收起 <<	Not Applicable	Completed	-	Iran, Islamic Republic of ... 展开 >> Hormozgan University of Medical Sciences (HUMS) Bandar abbas, Hormozgan, Iran, Islamic Republic of, 79145-3388 收起 <<
NCT00598572	Intracerebral Hemorrhage	Phase 1	Completed	-	United States, Massachusetts ... 展开 >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 收起 <<
NCT00061750	Beta-Thalassemia	Phase 3	Completed	-	United States, California ... 展开 >> Children's Hospital of Los Angeles Los Angeles, California, United States, 90027-6062 Children's Hospital Oakland Oakland, California, United States, 94609 Stanford Hospital Stanford, California, United States, 94305-5208 United States, Illinois Children's Memorial Hospital Chicago, Illinois, United States, 60614-3394 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 United States, New York Weill Medical College of Cornell University New York, New York, United States, 10021 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104-4318 收起 <<
NCT00110617	-		Completed	-	-
NCT02216513	Subarachnoid Hemorrhage	Early Phase 1	Terminated(Principle Investiga... 展开 >>tor is moving to another institution and plans to restart this proctocol in the new location.) 收起 <<	-	United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 收起 <<
NCT00870883	Hypotension A... 展开 >>cute Renal Failure 收起 <<	Phase 2	Completed	-	Brazil ... 展开 >> São José Hospital Criciuma, SC, Brazil, 88801250 收起 <<
NCT00738413	Thalassemia	Phase 1 Phase 2	Unknown	December 2009	United States, New York ... 展开 >> Weill Cornell Medical Center Recruiting New York, New York, United States, 10021 Contact: Robert W Grady, Ph.D. 212-746-3422 rwgrady@med.cornell.edu Contact: Kristen Muirhead, BS 212-746-3264 krm2066@med.cornell.edu Principal Investigator: Robert W Grady, Ph.D. Sub-Investigator: Patricia J Giardina, M.D. 收起 <<
NCT03085771	Diabetes Mellitus, Type 1	Phase 2	Recruiting	December 12, 2022	Sweden ... 展开 >> Karolinska University Hospital Recruiting Stockholm, Sweden, 17176 Contact: Sergiu Catrina, ass prof MD +46-8-51770000 sergiu-bogdan.Catrina@ki.se Contact: Neda Ekberg, PhD, MD +46-(0)8 51775449 Neda.Ekberg@ki.se 收起 <<
NCT01254227	Cardiac Iron Overload	Phase 2	Completed	-	Canada, Ontario ... 展开 >> Novartis Investigative Site Toronto, Ontario, Canada, M5G 2C4 Egypt Novartis Investigative Site Cairo, Egypt Greece Novartis Investigative Site Athens, GR, Greece, GR-115 27 Novartis Investigative Site Patra - RIO, GR, Greece, 265 04 Italy Novartis Investigative Site Cagliari, CA, Italy, 09121 Novartis Investigative Site Genova, GE, Italy, 16128 Novartis Investigative Site Napoli, Italy, 80138 Taiwan Novartis Investigative Site Taipei, Taiwan, 10002 Thailand Novartis Investigative Site Bangkok, Thailand, 10330 Novartis Investigative Site Bangkok, Thailand, 10700 Turkey Novartis Investigative Site Adana, Turkey, 01330 Novartis Investigative Site Antalya, Turkey, 07070 Novartis Investigative Site Istanbul, Turkey, 34093 Novartis Investigative Site Izmir, Turkey, 35040 United Kingdom Novartis Investigative Site London, United Kingdom, NW1 2BU 收起 <<
NCT00777140	Acute Ischemic Stroke	Phase 2	Completed	-	Spain ... 展开 >> Hospital Universitari Germans Trias i Pujol Badalona, Barcelona, Spain, 08916 Hospital Clínico Universitario de Santiago de Compostela Santiago de Compostela, La Coruña, Galicia, Spain, 15706 Hospital Universitari Josep Trueta Girona, Spain, 17007 Hospital Universitario de la Princesa Madrid, Spain, 28006 收起 <<
NCT02367248	Intracerebral Hemorrhage	Phase 1 Phase 2	Unknown	December 2016	China ... 展开 >> Department of Neurology，Beijing Shijitan Hospital，Capital Medical University Recruiting Beijing, China, 100038 Contact: Maolin He, MD 0086-010-63926550 maolinh@sina.com 收起 <<
NCT00658411	-		Terminated(Closed due to slow ... 展开 >>patient accrual) 收起 <<	-	-
NCT02875262	Intracranial Aneurysm ... 展开 >> Subarachnoid Hemorrhage 收起 <<	Phase 1 Phase 2	Not yet recruiting	June 1, 2018	Netherlands ... 展开 >> Radboudumc Not yet recruiting Nijmegen, Gelderland, Netherlands, 6500 HB Contact: Jeroen Boogaarts, M.D., Ph.D. 0031243615085 jeroen.boogaarts@radboudumc.nl Contact: Joost de Vries, M.D., Ph.D. 0031243615085 joost.devries@radboudumc.nl University Medical Center Groningen Not yet recruiting Groningen, Netherlands, 9713 GZ Contact: Marc van Dijk, M.D., Ph.,D. 00310503616161 j.m.c.van.dijk@umcg.nl Contact: Rob Groen, M.D., Ph.,D. 00310503616161 r.j.m.groen@umcg.nl 收起 <<
NCT00600938	-		Completed	-	-
NCT01662895	Intracerebral Hemorrhage	Phase 2	Suspended(By DSMB due to incre... 展开 >>ased incidence of ARDS. See modified protocol [NCT02175225) 收起 <<	December 2018	-
NCT02175225	Intracerebral Hemorrhage	Phase 2	Active, not recruiting	December 31, 2018	-
NCT00658411	Acute Myeloid Leukemia ... 展开 >> Acute Lymphoblastic Leukemia Myelodysplastic Syndrome 收起 <<	Not Applicable	Terminated(Closed due to slow ... 展开 >>patient accrual) 收起 <<	-	United States, Massachusetts ... 展开 >> Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 Dana-Farber Cancer Institute Boston, Massachusetts, United States, 02115 收起 <<
NCT03137966	Diabetic Foot Ulcer	Phase 2	Not yet recruiting	December 31, 2022	-
NCT03652467	Hepatocellular Carcinoma Non-r... 展开 >>esectable 收起 <<	Phase 1	Not yet recruiting	December 31, 2023	-

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