Capzimin
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货号：A433249
Capzimin shows > 5-fold selectivity for Rpn11 over the related JAMM proteases and > 2 logs selectivity over several other metalloenzymes.
Capzimin 化学结构
CAS号：2084868-04-0
Capzimin 3D分子结构
CAS号：2084868-04-0
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现货 |
1周
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Capzimin 纯度/质量文件 产品仅供科研
货号：A433249
标准纯度：
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Capzimin 质控信息
| PR-619 |
+
|
+++
UCH-L5, EC50: 12.8 μM
UCH-L3, EC50: 2.95 μM
|
+++
USP5, EC50: 4.90 μM
USP28, EC50: 6.24 μM
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99%+ |
| Degrasyn |
✔
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Bcr-Abl
|
98+% |
| VLX1570 |
+
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|
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|
99%+ |
| ML-323 |
++++
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99%+ |
| LDN-57444 |
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++++
UCH-L1, IC50: 0.4 μM
UCH-L3, IC50: 25 μM
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99%+ |
| TCID |
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++++
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98% |
| b-AP15 |
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+++
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98% |
| P 22077 |
|
|
++
USP7, IC50: 8.6 μM
USP47, EC50: 8.74 μM
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|
99%+ |
| P005091 |
|
|
++
USP47, IC50: 4.3 μM
USP7, EC50: 4.2 μM
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|
99+% |
| IU1 |
|
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++
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|
98% |
| NSC632839 |
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+
USP2, EC50: 45 μM
USP7, EC50: 37 μM
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99%+ |
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
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| Ixazomib |
++++
20S proteasome, Ki: 0.93 nM
20S proteasome, IC50: 3.4 nM
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|
|
99%+ |
| Delanzomib |
+++
Chymotrypsin-like proteasome, IC50: 3.8 nM
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|
|
98% |
| Celastrol |
+
20S proteasome, IC50: 2.5 μM
|
|
|
98% |
| MLN9708 |
+++
20S proteasome, Ki: 0.93 nM
20S proteasome, IC50: 3.4 nM
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99% |
| Bortezomib |
++++
20S proteasome, Ki: 0.6 nM
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98% |
| Oprozomib |
++
20S proteasome β5, IC50: 36 nM
20S proteasome LMP7, IC50: 82 nM
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|
|
99%+ |
| Epoxomicin |
✔
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|
95% |
| PI-1840 |
++
Chymotrypsin-like proteasome, IC50: 27 nM
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|
|
98% |
| VR23 |
|
+++
Chymotrypsin-like proteasomes, IC50: 3 μM
Trypsin-like proteasomes, IC50: 1 nM
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|
99% |
| Carfilzomib |
|
++
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|
98% |
| (R)-MG-132 |
|
+
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|
98% |
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
|
Capzimin 生物活性
| 描述 |
Capzimin shows > 5-fold selectivity for Rpn11 over the related JAMM proteases and > 2 logs selectivity over several other metalloenzymes. |
Capzimin 参考文献
Capzimin 实验方案
| 计算器 |
|
| 存储液制备 |
 |
1mg |
5mg |
10mg |
|
1 mM
5 mM
10 mM
|
1.59mL
0.32mL
0.16mL
|
7.95mL
1.59mL
0.80mL
|
15.90mL
3.18mL
1.59mL
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Capzimin 技术信息
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