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Benzyl benzoate/苯甲酸苯甲酯 {[allProObj[0].p_purity_real_show]}

货号:A954638 同义名: 苯甲酸苄酯 / Phenylmethyl benzoate; Ascabiol

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Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Benzyl benzoate/苯甲酸苯甲酯 化学结构 CAS号:120-51-4
Benzyl benzoate/苯甲酸苯甲酯 化学结构
CAS号:120-51-4
Benzyl benzoate/苯甲酸苯甲酯 3D分子结构
CAS号:120-51-4
Benzyl benzoate/苯甲酸苯甲酯 化学结构 CAS号:120-51-4
Benzyl benzoate/苯甲酸苯甲酯 3D分子结构 CAS号:120-51-4
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Benzyl benzoate/苯甲酸苯甲酯 纯度/质量文件 产品仅供科研

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Benzyl benzoate/苯甲酸苯甲酯 生物活性

描述 Benzyl benzoate, known chemically as Phenylmethyl benzoate, serves multiple roles including as an orally active anti-scabies agent and acaricide (with an EC50 of 0.06 g/m2), and as a fungicide. It also functions as an angiotensin II (Ang II) inhibitor, providing antihypertensive effects. Benzyl benzoate finds widespread use in perfumes, pharmaceuticals, and the food industry due to its efficacy and versatility[1].[2].[3].[4].[5].

Benzyl benzoate/苯甲酸苯甲酯 动物研究

Animal study Long-term administration of benzyl benzoate to rats (25-100 mg/kg orally, once daily for 90 days) shows no significant impact on body weight, relative organ weight, hematology, or biochemical markers. However, it induces pathological changes in the liver, kidney, thymus, prostate, and epididymal tissues of Sprague Dawley rats, highlighting potential risks associated with prolonged exposure[4].Benzyl benzoate, administered orally in a single dose ranging from 2 to 10 mg/kg, significantly counteracts hypertension induced by angiotensin II (Ang II), administered at a dose of 100 μg/kg, in Std:ddY mice. This effect underscores its potential as an antihypertensive agent[5].

Benzyl benzoate/苯甲酸苯甲酯 参考文献

[1]Bachewar NP, et al. Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies. Indian J Pharmacol. 2009 Feb;41(1):9-14.

[2]Raynaud S, et al. Squamocin and benzyl benzoate, acaricidal components of Uvaria pauci-ovulata bark extracts. Planta Med. 2000 Mar;66(2):173-5.

[3]Acar A, et al. Investigation of benzyl benzoate toxicity with anatomical, physiological, cytogenetic and biochemical parameters in in vivo[J]. Caryologia, 2020, 73(3).

[4]Kılıç Süloğlu A, et al. Toxicity of benzyl benzoate as a food additive and pharmaceutical agent. Toxicol Ind Health. 2022 Apr;38(4):221-233.

[5]Ohno O, et al. Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension. Bioorg Med Chem. 2008 Aug 15;16(16):7843-52.

Benzyl benzoate/苯甲酸苯甲酯 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.71mL

0.94mL

0.47mL

23.56mL

4.71mL

2.36mL

47.12mL

9.42mL

4.71mL

Benzyl benzoate/苯甲酸苯甲酯 技术信息

CAS号120-51-4
分子式C14H12O2
分子量 212.24
SMILES Code O=C(OCC1=CC=CC=C1)C2=CC=CC=C2
MDL No. MFCD00003075
别名 苯甲酸苄酯 ;Phenylmethyl benzoate; Ascabiol; Benzoic acid benzyl ester; Scabitox; Novoscabin
运输蓝冰
InChI Key SESFRYSPDFLNCH-UHFFFAOYSA-N
Pubchem ID 2345
存储条件

In solvent -20°C:3-6个月-80°C:12个月

溶解方案 请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
方案一
方案二
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