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首页 / 抑制剂/激动剂 / 抗感染 / Antiviral / Amitriptyline Impurity 1

Amitriptyline Impurity 1 {[allProObj[0].p_purity_real_show]}

货号：A795691

Dibenzosuberol may show effect of blocking rhinovirus replication in vitro

Amitriptyline Impurity 1 化学结构 CAS号：1210-34-0
Amitriptyline Impurity 1 化学结构
CAS号：1210-34-0
Amitriptyline Impurity 1 3D分子结构
CAS号：1210-34-0
Amitriptyline Impurity 1 化学结构 CAS号：1210-34-0
Amitriptyline Impurity 1 3D分子结构 CAS号：1210-34-0
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Amitriptyline Impurity 1 纯度/质量文件 产品仅供科研

货号：A795691 标准纯度： {[allProObj[0].p_purity_real_show]}
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Amitriptyline Impurity 1 生物活性

描述 A series of derivatives of dibenzofuran and dibenzosuberol block rhinovirus replication in vitro as judged by their ability to hinder the cytopathic effect in cells infected with HRV14 or HRV16. Both the number and the size of viral plaques were reduced effectively by treatment with these compounds in a dose-dependent fashion, thus affecting viral spread. Dibenzosuberenone showed minor differences in selectivity, with IC50 values of 10 and 30 microM for HRV16 and HRV14 cytopathy, respectively. Likewise, dibenzosuberenone effectively prevented the production of HRV16 proteins, viral RNA, and infectious virus particles when present at concentrations above 30 microM. Dibenzosuberenone can block the adsorption of viral particles on to cells, preventing further steps in the replication cycle, but is not effective as a direct inactivating agent[2].

Amitriptyline Impurity 1 参考文献

[1]Murray MA, Babe LM. Inhibitory effect of dibenzofuran and dibenzosuberol derivatives on rhinovirus replication in vitro; effective prevention of viral entry by dibenzosuberenone. Antiviral Res. 1999 Dec 15;44(2):123-31. doi: 10.1016/s0166-3542(99)00061-3. PMID: 10669262.

[2]Murray MA, Babe LM. Inhibitory effect of dibenzofuran and dibenzosuberol derivatives on rhinovirus replication in vitro; effective prevention of viral entry by dibenzosuberenone. Antiviral Res. 1999;44(2):123‐131

Amitriptyline Impurity 1 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.76mL

0.95mL

0.48mL

23.78mL

4.76mL

2.38mL

47.56mL

9.51mL

4.76mL

Amitriptyline Impurity 1 技术信息

CAS号1210-34-0
分子式C15H14O
分子量 210.27
SMILES Code OC1C2=CC=CC=C2CCC3=CC=CC=C13
MDL No. MFCD00003593
别名
运输蓝冰
InChI Key POAVRNPUPPJLKZ-UHFFFAOYSA-N
Pubchem ID 14588
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry, room temperature

Tags: Amitriptyline Impurity 1 |Amitriptyline Impurity 1 | 1210-34-0 | Antiviral | Amitriptyline Impurity 1 纯度/质量文件 | Amitriptyline Impurity 1 生物活性 | Amitriptyline Impurity 1 参考文献 | Amitriptyline Impurity 1 实验方案 | Amitriptyline Impurity 1 技术信息

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