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Amitraz/双甲脒 {[allProObj[0].p_purity_real_show]}

货号:A279484 同义名: BTS-27419; NSC 324552

Amitraz is a broad spectrum insecticide and acaricide which works as an α2 adrenergic agonist.

HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Amitraz/双甲脒 化学结构 CAS号:33089-61-1
Amitraz/双甲脒 化学结构
CAS号:33089-61-1
Amitraz/双甲脒 3D分子结构
CAS号:33089-61-1
Amitraz/双甲脒 化学结构 CAS号:33089-61-1
Amitraz/双甲脒 3D分子结构 CAS号:33089-61-1
规格 价格 会员价 库存 数量
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Amitraz/双甲脒 纯度/质量文件 产品仅供科研

货号:A279484 标准纯度: {[allProObj[0].p_purity_real_show]}
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。
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1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多,抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用,但抑制强度暂时没有相关数据。

Amitraz/双甲脒 生物活性

描述 Amitraz is a member of formamidine family of pesticides used as a veterinary ectoparasiticide (acaricide) for dogs and livestock, and as an agricultural insecticide for fruit crops[3]. Bee survival decreased in the 46 mg/L amitraz and 25 mg/L coumaphos treatments but not in any fluvalinate treatment. Furthermore, the developmental rate decreased in individuals treated with 46 mg/L amitraz[4]. Moreover, polymorphisms in the RmβAOR gene( β-adrenergic octopamine receptor gene) are likely to confer resistance to amitraz[5].

Amitraz/双甲脒 参考文献

[1]del Pino J, Moyano-Cires PV, et al. Molecular mechanisms of amitraz mammalian toxicity: a comprehensive review of existing data. Chem Res Toxicol. 2015 Jun 15;28(6):1073-94.

[2]Pekmezci D, Pekmezci GZ, et al. Efficacy of amitraz plus inactivated parapoxvirus ovis in the treatment of canine generalised demodicosis. Vet Rec. 2014 May 31;174(22):556.

[3]Dhooria S, Agarwal R. Amitraz, an underrecognized poison: A systematic review. Indian J Med Res. 2016 Sep;144(3):348-358. doi: 10.4103/0971-5916.198723. PMID: 28139533; PMCID: PMC5320840.

[4]Dai P, Jack CJ, Mortensen AN, Bustamante TA, Ellis JD. Chronic toxicity of amitraz, coumaphos and fluvalinate to Apis mellifera L. larvae reared in vitro. Sci Rep. 2018 Apr 4;8(1):5635. doi: 10.1038/s41598-018-24045-3. PMID: 29618776; PMCID: PMC5884784.

[5]Corley SW, Jonsson NN, Piper EK, Cutullé C, Stear MJ, Seddon JM. Mutation in the RmβAOR gene is associated with amitraz resistance in the cattle tick Rhipicephalus microplus. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16772-7. doi: 10.1073/pnas.1309072110. Epub 2013 Sep 30. PMID: 24082133; PMCID: PMC3801038.

Amitraz/双甲脒 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.41mL

0.68mL

0.34mL

17.04mL

3.41mL

1.70mL

34.08mL

6.82mL

3.41mL

Amitraz/双甲脒 技术信息

CAS号33089-61-1
分子式C19H23N3
分子量 293.41
SMILES Code CN(/C=N/C1=CC=C(C)C=C1C)/C=N/C2=CC=C(C)C=C2C
MDL No. MFCD00069396
别名 BTS-27419; NSC 324552; U 36059; Ovasyn; Taktic; Mitaban
运输蓝冰
InChI Key QXAITBQSYVNQDR-UHFFFAOYSA-N
Pubchem ID 36324
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry, store in freezer, under -20°C

溶解方案 请根据您的动物给药指南选择适当的溶解方案。
以下溶解方案都请先按照体外实验的方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议现用现配,当天使用; 以下溶剂前显示的百分比是指该溶剂在终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶
方案一
方案二
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