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/ 4-Chloro-3,5-dimethylphenol/氯二甲酚

4-Chloro-3,5-dimethylphenol/氯二甲酚 {[allProObj[0].p_purity_real_show]}

货号：A139376 同义名： 氯二甲酚;对氯间二甲酚 / p-chloro-m-xylenol; Chloroxylenol

Chloroxylenol is an antiseptic and disinfectant which is used for skin disinfection and cleaning surgical instruments.

4-Chloro-3,5-dimethylphenol/氯二甲酚 化学结构 CAS号：88-04-0
4-Chloro-3,5-dimethylphenol/氯二甲酚 化学结构
CAS号：88-04-0
4-Chloro-3,5-dimethylphenol/氯二甲酚 3D分子结构
CAS号：88-04-0
4-Chloro-3,5-dimethylphenol/氯二甲酚 化学结构 CAS号：88-04-0
4-Chloro-3,5-dimethylphenol/氯二甲酚 3D分子结构 CAS号：88-04-0
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4-Chloro-3,5-dimethylphenol/氯二甲酚 纯度/质量文件 产品仅供科研

货号：A139376 标准纯度： {[allProObj[0].p_purity_real_show]}
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4-Chloro-3,5-dimethylphenol/氯二甲酚 生物活性

描述 Chloroxylenol is an antimicrobial ingredient that is frequently used in antiseptics/disinfectants for skin (e.g. hand soap) and non-living surfaces[3]. Triclosan and chloroxylenol decrease the degree of fluidity of membranes and this effect is more pronounced in bacterial membranes[4]. The toxicological data for chloroxylenol indicate lack of genotoxicity, no evidence of carcinogenicity, and minimal systemic toxicity[5]. Treatment of S. aureus with the antiseptic chloroxylenol alone did not decrease biofilm cell viability; however, the combination of chloroxylenol and P. aeruginosa supernatant led to a 4-log reduction in S. aureus biofilm viability compared to exposure to chloroxylenol alone[6].

4-Chloro-3,5-dimethylphenol/氯二甲酚 临床研究

NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT02139033 Keratoconjunctivitis Sicca Phase 4 Completed - United States, Massachusetts ... 展开 >> Andover, Massachusetts, United States, 01810 收起 <<
NCT01521507 Meibomian Gland Dysfunction ... 展开 >> Dry Eye 收起 << Not Applicable Completed - United States, Arkansas ... 展开 >> McDonald Eye Associates Fayetteville, Arkansas, United States, 72703 United States, California Harvard Eye Associates Laguna Hills, California, United States, 92653 United States, Florida Center for Excellence in Eye Care Miami, Florida, United States, 33176 United States, Illinois Chicago Cornea Consultants, Ltd. Hoffman Estates, Illinois, United States, 60169 Jackson Eye Lake Villa, Illinois, United States, 50046 United States, Kentucky Cincinnati Eye Institute - Northern Kentucky Edgewood, Kentucky, United States, 41017 United States, Massachusetts Charles River Eye Associates Winchester, Massachusetts, United States, 01890 United States, Minnesota Associated Eye Care Stillwater, Minnesota, United States, 55082 United States, Missouri Ophthalmology Consultants, Ltd. St. Louis, Missouri, United States, 63131 收起 <<
NCT01521507 - Completed - -

4-Chloro-3,5-dimethylphenol/氯二甲酚 参考文献

[1]Gatti R, Roveri P, et al. HPLC-fluorescence determination of chlorocresol and chloroxylenol in pharmaceuticals. J Pharm Biomed Anal. 1997 Nov;16(3):405-12.

[2]Aly R, Maibach HI. Comparative antibacterial efficacy of a 2-minute surgical scrub with chlorhexidine gluconate, povidone-iodine, and chloroxylenol sponge-brushes. Am J Infect Control. 1988 Aug;16(4):173-7.

[3]Choi D, Oh S. Removal of Chloroxylenol Disinfectant by an Activated Sludge Microbial Community. Microbes Environ. 2019;34(2):129–135

[4]Poger D, Mark AE. Effect of Triclosan and Chloroxylenol on Bacterial Membranes. J Phys Chem B. 2019;123(25):5291–5301

[5]Yost LJ, Rodricks JD, Turnbull D, et al. Human health risk assessment of chloroxylenol in liquid hand soap and dishwashing soap used by consumers and health-care professionals. Regul Toxicol Pharmacol. 2016;80:116–124

[6]Orazi G, Ruoff KL, O'Toole GA. Pseudomonas aeruginosa Increases the Sensitivity of Biofilm-Grown Staphylococcus aureus to Membrane-Targeting Antiseptics and Antibiotics. mBio. 2019;10(4):e01501-19.

4-Chloro-3,5-dimethylphenol/氯二甲酚 实验方案

计算器
存储液制备 1mg 5mg 10mg

1 mM

5 mM

10 mM

6.39mL

1.28mL

0.64mL

31.93mL

6.39mL

3.19mL

63.85mL

12.77mL

6.39mL

4-Chloro-3,5-dimethylphenol/氯二甲酚 技术信息

CAS号88-04-0
分子式C8H9ClO
分子量 156.61
SMILES Code CC1=CC(O)=CC(C)=C1Cl
MDL No. MFCD00002324
别名 氯二甲酚;对氯间二甲酚;4-氯-3,5-二甲基苯酚;酚洁新PX ;p-chloro-m-xylenol; Chloroxylenol; HSDB7427
运输蓝冰
InChI Key OSDLLIBGSJNGJE-UHFFFAOYSA-N
Pubchem ID 2723
存储条件

In solvent -20°C:3-6个月-80°C:12个月

Pure form Sealed in dry,2-8°C

Tags: Chloroxylenol | 88-04-0 | p-chloro-m-xylenol | Anti-infection | Bacterial | Influenza Virus | Parasite | 仅供科研使用 | AmBeed-信号通路专用抑制剂 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 纯度/质量文件 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 生物活性 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 临床数据 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 参考文献 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 实验方案 | 4-Chloro-3,5-dimethylphenol/氯二甲酚 技术信息

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