ABP688
产品说明书
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同义名 : | - |
| CAS号 : | 924298-51-1 | |
| 货号 : | A998571 | |
| 分子式 : | C15H16N2O | |
| 纯度 : | 98%+ | |
| 分子量 : | 240.3 | |
| MDL号 : | MFCD17018722 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | ABP688 is a high affinity human mGluR5 antagonist with a Ki value of 1.7 nM. Radioisotope-labelled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5 receptor[1]. | ||
| 临床研究 | |||||
|---|---|---|---|---|---|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
| NCT02727972 | Major Depressive Disorder ... 展开 >> Post-Traumatic Stress Disorder Bipolar Disorder 收起 << | Not Applicable | Recruiting | August 2020 | United States, Connecticut ... 展开 >> PET Center Recruiting New Haven, Connecticut, United States, 06519 Contact: Sarah O, MA 203-737-7066 Principal Investigator: Irina Esterlis, PhD 收起 << |
| NCT01691092 | Major Depressive Disorder ... 展开 >> Post-Traumatic Stress Disorder (PTSD) 收起 << | Not Applicable | Completed | - | United States, Connecticut ... 展开 >> Connecticut Mental Health Center New Haven, Connecticut, United States, 06519 Yale University Magnetic Resonance Research Center (MRRC) New Haven, Connecticut, United States, 06519 Yale University PET Center New Haven, Connecticut, United States, 06519 收起 << |
| NCT01528241 | Depression | Phase 1 | Completed | - | United States, New York ... 展开 >> Novartis Investigative Site New York, New York, United States United States, Pennsylvania Novartis Investigative Site Pittsburgh, Pennsylvania, United States 收起 << |
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
4.16mL 0.83mL 0.42mL |
20.81mL 4.16mL 2.08mL |
41.61mL 8.32mL 4.16mL |
