Dihydroresveratrol
产品说明书
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同义名 : | 二氢藜芦醇 ;3,4',5-Trihydroxybibenzyl; α,β-Dihydro-3,4',5-trihydroxystilbene; DHRSV |
| CAS号 : | 58436-28-5 | |
| 货号 : | A976087 | |
| 分子式 : | C14H14O3 | |
| 纯度 : | 99%+ | |
| 分子量 : | 230.26 | |
| MDL号 : | MFCD25973128 | |
| 存储条件： |
Pure form Keep in dark place,Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Dihydroresveratrol has been identified as a phytoalexin in Orchidaceae, in Cannabis sativaL., and in the tuber of Dioscorea dumetorum, where its production seems to be elicited by fungal infection[2]. As a well-known metabolite of transresveratrol formed in the intestine, dihydroresveratrol is a potent phytoestrogen that acts as a hormone receptor modulator. Dihydroresveratrol demonstrated strong proliferative properties in hormone-dependent cell lines (such as MCF-7) at picomolar (10-12 M) concentrations. At high concentrations (1×10-5 to 1×10-3 M), dihydroresveratrol showed a typical decrease in the growth rate of both PC-3 prostate cancer cells and DU-145 tumor cells. However, treatment with 1×10-10 to 1×10-8 M of dihydroresveratrol significantly increased the growth of both the same cells indicating dihydroresveratrol having a biphasic effect[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
4.34mL 0.87mL 0.43mL |
21.71mL 4.34mL 2.17mL |
43.43mL 8.69mL 4.34mL |
| 参考文献 |
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