同义名 :	-
	CAS号 :	943540-74-7
	货号 :	A967658
	分子式 :	C20H12F2N6
	纯度 :	99%
	分子量 :	374.35
	MDL号 :	MFCD31657377
	存储条件：	Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	JNJ-38877618 is a potent, highly selective, orally bioavailable Met kinase inhibitor with IC50s of 2 and 3 nM for wild type and mutant Met, respectively.

临床研究
NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01964872	Healthy Volunteers	Phase 1	Completed	-	United Kingdom ... 展开 >> Nottingham, United Kingdom 收起 <<
NCT03138083	Neoplasms	Phase 1 Phase 2	Recruiting	December 2020	France ... 展开 >> lNSTITUT GUSTAVE ROUSSY Recruiting Villejuif, France, 94805 Contact: Eric Angevin, MD          Netherlands Erasmus Mc Recruiting Rotterdam, Netherlands, 3000 CA Contact: Martijn Lolkema, MD/PhD          Universitair Medisch Centrum Utrecht Recruiting Utrecht, Netherlands, 3584 CX Contact: Filip De Vos, MD          United Kingdom University College London Hospitals Nhs Foundation Trust Recruiting London, United Kingdom, NW1 2BU Contact: Martin Forster, MD          The Christie Nhs Foundation Trust Recruiting Manchester, United Kingdom, M20 4BX Contact: Matthew G Krebs, MD PhD MRCP       Matthew.Krebs@christie.nhs.uk    The Newcastle Upon Tyne Hospitals Nhs Foundation Trust Recruiting Newcastle upon Tyne, United Kingdom, NE7 7DN Contact: Ruth Plummer, MD       Ruth.Plummer@newcastle.ac.uk    University of Oxford, Department of Oncology Recruiting Oxford, United Kingdom, OX3 7LE Contact: Sarah P Blagden, MD    +441865227212    sarah.blagden@oncology.ox.ac.uk 收起 <<

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.67mL 0.53mL 0.27mL	13.36mL 2.67mL 1.34mL	26.71mL 5.34mL 2.67mL