Benzyl benzoate

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Chemical Structure| 120-51-4 同义名 : 苯甲酸苄酯 ;Phenylmethyl benzoate; Ascabiol; Benzoic acid benzyl ester; Scabitox; Novoscabin
CAS号 : 120-51-4
货号 : A954638
分子式 : C14H12O2
纯度 : 99%
分子量 : 212.24
MDL号 : MFCD00003075
存储条件：

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Benzyl benzoate, known chemically as Phenylmethyl benzoate, serves multiple roles including as an orally active anti-scabies agent and acaricide (with an EC50 of 0.06 g/m2), and as a fungicide. It also functions as an angiotensin II (Ang II) inhibitor, providing antihypertensive effects. Benzyl benzoate finds widespread use in perfumes, pharmaceuticals, and the food industry due to its efficacy and versatility[1].[2].[3].[4].[5].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.71mL

0.94mL

0.47mL

23.56mL

4.71mL

2.36mL

47.12mL

9.42mL

4.71mL
参考文献

[1]Bachewar NP, et al. Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies. Indian J Pharmacol. 2009 Feb;41(1):9-14.

[2]Raynaud S, et al. Squamocin and benzyl benzoate, acaricidal components of Uvaria pauci-ovulata bark extracts. Planta Med. 2000 Mar;66(2):173-5.

[3]Acar A, et al. Investigation of benzyl benzoate toxicity with anatomical, physiological, cytogenetic and biochemical parameters in in vivo[J]. Caryologia, 2020, 73(3).

[4]Kılıç Süloğlu A, et al. Toxicity of benzyl benzoate as a food additive and pharmaceutical agent. Toxicol Ind Health. 2022 Apr;38(4):221-233.

[5]Ohno O, et al. Inhibitory effects of benzyl benzoate and its derivatives on angiotensin II-induced hypertension. Bioorg Med Chem. 2008 Aug 15;16(16):7843-52.