同义名 :	EPZ020411 2HCl; EPZ020411 hydrochloride
	CAS号 :	2070015-25-5
	货号 :	A949907
	分子式 :	C25H39ClN4O3
	纯度 :	99%
	分子量 :	479.06
	MDL号 :	MFCD29924736
	存储条件：	Pure form Inert atmosphere,2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	EPZ020411 hydrochloride is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has > 10 fold selectivity for PRMT6 over PRMT1 and PRMT8.

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.09mL 0.42mL 0.21mL	10.44mL 2.09mL 1.04mL	20.87mL 4.17mL 2.09mL

参考文献
[1]Mitchell LH, Drew AE, et al. Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound. ACS Med Chem Lett. 2015 Apr 6;6(6):655-9.