Aderbasib

产品说明书

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Chemical Structure| 791828-58-5 同义名 : INCB7839; INCB007839
CAS号 : 791828-58-5
货号 : A938154
分子式 : C21H28N4O5
纯度 : 98%
分子量 : 416.47
MDL号 : MFCD13195569
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Aderbasib is a sheddase inhibitor, is also an orally bioavailable inhibitor of the ADAM (A disintegrin and metalloprotease) family of multifunctional membrane-bound proteins with potential antineoplastic activity.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

12.01mL

2.40mL

1.20mL

24.01mL

4.80mL

2.40mL
参考文献

[1]Witters L, Scherle P, et al. Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor. Cancer Res. 2008 Sep 1;68(17):7083-9.