IRAK-4 protein kinase inhibitor 2

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Chemical Structure| 301675-24-1 同义名 : -
CAS号 : 301675-24-1
货号 : A927418
分子式 : C14H10N4O3
纯度 : 99%+
分子量 : 282.25
MDL号 : MFCD01006950
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 IRAK-4 protein kinase inhibitor 2 is a potent inhibitor of interleukin-1 receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. It is suitable for research into inflammatory and immune-related conditions or disorders[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.54mL

0.71mL

0.35mL

17.71mL

3.54mL

1.77mL

35.43mL

7.09mL

3.54mL
参考文献

[1]Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.