δ-Amyrenone

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Chemical Structure| 20248-08-2 同义名 : Delta-Amyrone
CAS号 : 20248-08-2
货号 : A893152
分子式 : C30H48O
纯度 : 99+%
分子量 : 424.7
MDL号 : MFCD20260471
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 13(18)-Oleanen-3-one is a natural product isolated and purified from the herbs of Euphorbia supina with anti-inflammatory effect, which can inhibit IL-6, TNF-α and NO production, control the cyclooxygenase-2 (COX-2) regulation at protein levels.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.24mL

11.77mL

2.35mL

1.18mL

23.55mL

4.71mL

2.35mL
参考文献

[1]Niu X, Yao H, et al. δ-Amyrone inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice. Chem Biol Interact. 2015 Oct 5;240:354-61.

[2]Niu X, Yao H, et al. δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice. Int Immunopharmacol. 2014 Jul;21(1):112-8.