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同义名 : | (2R)-Octyl-2-HG |
CAS号 : | 1391194-67-4 | |
货号 : | A888839 | |
分子式 : | C13H24O5 | |
纯度 : | 97% | |
分子量 : | 260.33 | |
MDL号 : | MFCD30735809 | |
存储条件: |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | (2R)-Octyl-α-hydroxyglutarate is a modified form of 2-Hydroxyglutarate with high cellular uptake. Treatment of IDH1-WT HeLa cells with (2R)-Octyl-α-hydroxyglutarate leads to an increase in DSBs in log phase cells in a dose-dependent manner. It has been used to study the contribution of D-2-hydroxyglutarate to mitochondrial oxidative processes in IDH1 mutant cancer cells[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
3.84mL 0.77mL 0.38mL |
19.21mL 3.84mL 1.92mL |
38.41mL 7.68mL 3.84mL |