DM1-SMe
产品说明书
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同义名 : | - |
| CAS号 : | 138148-68-2 | |
| 货号 : | A866930 | |
| 分子式 : | C36H50ClN3O10S2 | |
| 纯度 : | 98%+ | |
| 分子量 : | 784.38 | |
| MDL号 : | MFCD28400100 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | DM1-SMe, the unconjugated Maytansinoid present in IMGN901, exhibits significantly enhanced potency—approximately 3-10 times greater—than its progenitor compound, Maytansine. The IC50 values for DM1-SMe span from 0.003 to 0.01 nM across various human tumor cell lines[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.27mL 0.25mL 0.13mL |
6.37mL 1.27mL 0.64mL |
12.75mL 2.55mL 1.27mL |
