同义名 :	-
	CAS号 :	7421-40-1
	货号 :	A862176
	分子式 :	C34H48Na2O7
	纯度 :	98%
	分子量 :	614.72
	MDL号 :	MFCD03840711
	存储条件：	Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Carbenoxolone disodium, derived from Glycyrrhizic acid, acts as an inhibitor of both human 11β-HSD and bacterial 3α, 20β-HSD enzymes[1]. Carbenoxolone disodium also serves as an uncoupling agent for gap junctions and effectively inhibits the replication of Vaccinia virus[2].

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	1.63mL 0.33mL 0.16mL	8.13mL 1.63mL 0.81mL	16.27mL 3.25mL 1.63mL

参考文献

[1]W L Duax, et al. Steroid Dehydrogenase Structures, Mechanism of Action, and Disease. Vitam Horm. 2000;58:121-48. [2]Hossein Hosseinzadeh, et al. Anticonvulsant, Sedative and Muscle Relaxant Effects of Carbenoxolone in Mice. BMC Pharmacol. 2003 Apr 29;3:3. [3]Ismar R Haga, et al. Carbenoxolone-mediated Cytotoxicity Inhibits Vaccinia Virus Replication in a Human Keratinocyte Cell Line. Sci Rep. 2018 Nov 16;8(1):16956.