Pyroxamide

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Chemical Structure| 382180-17-8 同义名 : -
CAS号 : 382180-17-8
货号 : A849824
分子式 : C13H19N3O3
纯度 : 99%
分子量 : 265.31
MDL号 : MFCD13194970
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Pyroxamide is a robust inhibitor of histone deacetylase 1 (HDAC1), exhibiting an IC50 of 100 nM. It has the capability to induce apoptosis and cell cycle arrest in leukemia[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.77mL

0.75mL

0.38mL

18.85mL

3.77mL

1.88mL

37.69mL

7.54mL

3.77mL
参考文献

[1]Butler LM, et al. Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase. Clin Cancer Res. 2001 Apr;7(4):962-70.