ARN2966

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Chemical Structure| 102212-26-0 同义名 : 2-PMAP
CAS号 : 102212-26-0
货号 : A823864
分子式 : C12H12N2O
纯度 : 99%
分子量 : 200.24
MDL号 : MFCD24550644
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 ARN2966 is a potent post-transcriptional modulator of APP expression and reduces expression of APP with resultant lower production of Aβ.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.99mL

1.00mL

0.50mL

24.97mL

4.99mL

2.50mL

49.94mL

9.99mL

4.99mL
参考文献

[1]Asuni AA, Guridi M, et al. Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model. Ann Neurol. 2014 May;75(5):684-99.

[2]Wong YL, Ng DK, Lee HK. New chloro, mu-oxo, and alkyl derivatives of dioxomolybdenum(VI) and -tungsten(VI) complexes chelated with N(2)O tridentate ligands: synthesis and catalytic activities toward olefin epoxidation. Inorg Chem. 2002 Oct 7;41(20):5276-85.