TNKS-2-IN-1

产品说明书

Print
Chemical Structure| 4765-59-7 同义名 : -
CAS号 : 4765-59-7
货号 : A819693
分子式 : C14H9N3O3
纯度 : 98%+
分子量 : 267.24
MDL号 : MFCD28157558
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 TNKS-2-IN-1 functions as an inhibitor of TNKS-2, exhibiting inhibitory effects on both TNKS-1 and TNKS-2 with IC50 values of 259 nM and 1100 nM, respectively[1].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

3.74mL

0.75mL

0.37mL

18.71mL

3.74mL

1.87mL

37.42mL

7.48mL

3.74mL
参考文献

[1]Nathubhai A, et al. Structure-activity relationships of 2-arylquinazolin-4-ones as highly selective and potent inhibitors of the tankyrases. Eur J Med Chem. 2016 Aug 8;118:316-27.