USP7-IN-1
产品说明书
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同义名 : | - |
| CAS号 : | 1381291-36-6 | |
| 货号 : | A794659 | |
| 分子式 : | C23H24ClN3O3 | |
| 纯度 : | 99% | |
| 分子量 : | 425.91 | |
| MDL号 : | MFCD28385846 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | USP7-IN-1 is a selective and reversible USP7 inhibitor, characterized by an IC50 of 77 μM, demonstrating specificity as it does not inhibit USP8, USP5, Uch-L1, Uch-L3, or caspase 3. Its anti-proliferative effects are observed in HCT116 cells, where it has a GI50 of 67 μM[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.35mL 0.47mL 0.23mL |
11.74mL 2.35mL 1.17mL |
23.48mL 4.70mL 2.35mL |
| 参考文献 |
|---|
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[1]SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1 |