CPPHA

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Chemical Structure| 693288-97-0 同义名 : -
CAS号 : 693288-97-0
货号 : A784614
分子式 : C22H15ClN2O4
纯度 : 99%
分子量 : 406.82
MDL号 : MFCD12912405
存储条件:

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 CPPHA is a selective positive allosteric modulator of mGluR5 receptor.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.46mL

0.49mL

0.25mL

12.29mL

2.46mL

1.23mL

24.58mL

4.92mL

2.46mL

参考文献

[1]Liu F, Zhang G, et al. The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices. Eur J Pharmacol. 2006 May 1;536(3):262-8.

[2]O'Brien JA, Lemaire W, et al. A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain. J Pharmacol Exp Ther. 2004 May;309(2):568-77.