CMPD1
产品说明书
 |
同义名 : | MK2a Inhibitor |
| CAS号 : | 41179-33-3 | |
| 货号 : | A784195 | |
| 分子式 : | C22H20FNO2 | |
| 纯度 : | 97% | |
| 分子量 : | 349.4 | |
| MDL号 : | MFCD08703098 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | CMPD1 is a selective, non-ATP-competitive inhibitor of p38 MAPK-mediated MK2 phosphorylation with a Kiapp of 330 nM[1][2].CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of the other two substrates (MBP and ATF2). CMPD1 induces mitotic arrest and apoptosis in U87 cells[1].CMPD1 inhibits microtubule protein polymerisation in glioblastoma cells[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.86mL 0.57mL 0.29mL |
14.31mL 2.86mL 1.43mL |
28.62mL 5.72mL 2.86mL |
