Balsalazide

产品说明书

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Chemical Structure| 80573-04-2 同义名 : Colazal; Giazo
CAS号 : 80573-04-2
货号 : A759393
分子式 : C17H15N3O6
纯度 : 98+%
分子量 : 357.32
MDL号 : MFCD00868204
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00269438 Ulcerative Colitis Phase 3 Completed - -
NCT00486031 Inflammatory Bowel Disease ... 展开 >> Ulcerative Colitis 收起 << Phase 3 Completed - -
NCT00486031 - Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.80mL

0.56mL

0.28mL

13.99mL

2.80mL

1.40mL

27.99mL

5.60mL

2.80mL
参考文献

[1]Wiggins JB, Rajapakse R. Balsalazide: a novel 5-aminosalicylate prodrug for the treatment of active ulcerative colitis. Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1279-84.

[2]Kruis W, Schreiber S, et al. Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses. Gut. 2001 Dec;49(6):783-9.