L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate
产品说明书
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同义名 : | L-Ascorbic acid 2-phosphate magnesium; 2-Phospho-L-ascorbic acid magnesium; L-Ascorbic acid 2-phosphate sesquimagnesium salt |
| CAS号 : | 113170-55-1 | |
| 货号 : | A757954 | |
| 分子式 : | C12H18Mg3O18P2 | |
| 纯度 : | 98% | |
| 分子量 : | 585.12 | |
| MDL号 : | MFCD11045932 | |
| 存储条件： |
Pure form Sealed in dry,2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate is a vitamin derivative that stimulates collagen formation and expression[1].L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate can be used as a medium supplement for osteogenic differentiation of human adipose stem cells (hASCs). During osteogenic differentiation, L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate increased alkaline phosphatase (ALP) activity and runx2A expression in human adipose stem cells[2][3].The addition of L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate significantly stimulated cell growth while the addition of L-ascorbic acid (Asc) only achieved weak growth stimulation at concentrations of 0.1-1.5 mM with medium changes every 2 to 3 days for 2-3 weeks[1].Effective osteogenic differentiation of human adipose stem cells (hASCs) requires L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate (50 µM-250 µM), and higher concentrations of AsA2-P increase runx2 expression and ALP activity. 150 µM AsA2-P and 10 nM concentration of dexamethasone and 250 µM AsA2-P or 5 nM concentration of dexamethasone resulted in the highest proliferation, ALP activity and runx2 expression[3]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.71mL 0.34mL 0.17mL |
8.55mL 1.71mL 0.85mL |
17.09mL 3.42mL 1.71mL |
