Hydroxyzine pamoate

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Chemical Structure| 10246-75-0 同义名 : 拉姆酸羟嗪
CAS号 : 10246-75-0
货号 : A756182
分子式 : C44H43ClN2O8
纯度 : 98%
分子量 : 763.27
MDL号 : MFCD00058051
存储条件:

Pure form Sealed in dry, room temperature

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Hydroxyzine pamoate is a histamine H1-receptor antagonist.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT00332163 Metastatic Colorectal Cancer ... 展开 >> Skin Rash Skin Toxicities Colon Cancer Colorectal Cancer 收起 << Phase 2 Completed - -
NCT02797522 Hepatitis B Phase 1 Terminated(Company decision to... 展开 >> discontinue trial) 收起 << - New Zealand ... 展开 >> Auckland Clinical Studies Ltd Grafton, Auckland, New Zealand, 1011 收起 <<
NCT02797522 - Terminated(Company decision to... 展开 >> discontinue trial) 收起 << - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.31mL

0.26mL

0.13mL

6.55mL

1.31mL

0.66mL

13.10mL

2.62mL

1.31mL

参考文献

[1]Kan WM, Liu YT, et al. Effect of hydroxyzine on the transport of etoposide in rat small intestine. Anticancer Drugs. 2001 Mar;12(3):267-73.

[2]Minogiannis P, El-Mansoury M, et al. Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol. 1998 Oct;20(10):553-63.