NH2-PEG6-Boc

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Chemical Structure| 1286281-32-0 同义名 : -
CAS号 : 1286281-32-0
货号 : A754913
分子式 : C19H39NO8
纯度 : 95%
分子量 : 409.51
MDL号 : MFCD13184944
存储条件：

Pure form Keep in dark place, inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 NH2-PEG6-Boc is a PEG-derived linker suitable for synthesizing PROTACs [1]. NH2-PEG6-Boc is also a non-cleavable ADC linker comprised of a 6-unit PEG, employed in the synthesis of antibody-drug conjugates (ADCs) [2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.44mL

0.49mL

0.24mL

12.21mL

2.44mL

1.22mL

24.42mL

4.88mL

2.44mL
参考文献

[1]Foley CA, et al. Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay. ACS Chem Biol. 2020 Jan 17;15(1):290-295.

[2]Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1.