Carboxyamidotriazole

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Chemical Structure| 99519-84-3 同义名 : L-651582; CAI; RFE-007; NSC 609974
CAS号 : 99519-84-3
货号 : A753409
分子式 : C17H12Cl3N5O2
纯度 : 95%
分子量 : 424.67
MDL号 : MFCD00866325
存储条件：

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 Carboxyamidotriazole (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways, which shows anti-tumor, anti-inflammatory and antiangiogenic effects[1].[2].
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.35mL

0.47mL

0.24mL

11.77mL

2.35mL

1.18mL

23.55mL

4.71mL

2.35mL
参考文献

[1]Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229.

[2]Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.