ML-098
产品说明书
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同义名 : | CID-7345532 |
| CAS号 : | 878978-76-8 | |
| 货号 : | A736431 | |
| 分子式 : | C19H19NO3 | |
| 纯度 : | 99% | |
| 分子量 : | 309.36 | |
| MDL号 : | MFCD08672264 | |
| 存储条件： |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | ML-098 (CID-7345532) operates by enhancing the affinity of the GTPases for guanine nucleotides, suggesting that these activators interact with allosteric binding sites situated between switch regions I and II. ML-098 serves as an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM, displaying selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (with EC50s of 588.8, 346.7, 158.5, and 794.3 nM, respectively) [1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
3.23mL 0.65mL 0.32mL |
16.16mL 3.23mL 1.62mL |
32.32mL 6.46mL 3.23mL |
| 参考文献 |
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