Ximelagatran
产品说明书
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同义名 : | H 376/95; Exanta; Exarta; H 376-95 |
| CAS号 : | 192939-46-1 | |
| 货号 : | A734242 | |
| 分子式 : | C24H35N5O5 | |
| 纯度 : | 98%+ | |
| 分子量 : | 473.57 | |
| MDL号 : | MFCD05861056 | |
| 存储条件： |
Pure form Inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
|
| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | Ximelagatran is an orally active thrombin inhibitor that selectively and competitively inhibits free or clot-bound thrombin. Ximelagatran can be used as an anticoagulant with rapid onset of action, predictable, dose-dependent pharmacokinetic and pharmacodynamic properties[1][2].Ximelagatran is currently being used in the development of anticoagulants for the prevention and treatment of thromboembolism. Ximelagatran is rapidly absorbed and rapidly converted to its active form, Melagatran. Preliminary studies have demonstrated the efficacy and safety of Ximelagatran in the prevention of venous thromboembolism following total knee or total hip arthroplasty[3]. . | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
|
1 mM 5 mM 10 mM |
2.11mL 0.42mL 0.21mL |
10.56mL 2.11mL 1.06mL |
21.12mL 4.22mL 2.11mL |
