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同义名 : | - |
CAS号 : | 439144-66-8 | |
货号 : | A724374 | |
分子式 : | C15H8BrF6NO2 | |
纯度 : | 99%+ | |
分子量 : | 428.12 | |
MDL号 : | MFCD31630827 | |
存储条件: |
Pure form Sealed in dry, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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溶解度 : | - | |
动物实验配方: |
生物活性 | |||
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描述 | IMD-0560 is a novel IκB kinase β inhibitor. Pretreatment with IMD-0560 inhibited TNFα-induced IκBα degradation and p65 phosphorylation. IMD-0560 also inhibited TNFα-induced transcriptional activity. Pretreatment with IMD-0560 strongly inhibited TNFα-induced cell invasion. IMD-0560 inhibits the activity of MMP-9 by suppressing its expression[1]. |
实验方案 | |||
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1mg | 5mg | 10mg | |
1 mM 5 mM 10 mM |
2.34mL 0.47mL 0.23mL |
11.68mL 2.34mL 1.17mL |
23.36mL 4.67mL 2.34mL |