CA-170
产品说明书
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同义名 : | Pd-1-in-1; AUPM-170; Aurigene 1; PD1-IN-1. PD-L1/PD-L2/VISTA antagonist; PD-1-IN17; PD-1-IN-1 free base |
| CAS号 : | 1673534-76-3 | |
| 货号 : | A723757 | |
| 分子式 : | C12H20N6O7 | |
| 纯度 : | 97% (contains 2.7% ethanol) | |
| 分子量 : | 360.32 | |
| MDL号 : | MFCD30738000 | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, 2-8°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
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| 靶点 |
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| 描述 | CA-170 is an oral inhibitor targeting both VISTA and PD-L1. It effectively restores the proliferative and effector capabilities of T cells that are suppressed by PD-L1/L2 and VISTA. CA-170 is selective, favoring these immune checkpoints over a wide array of other immune proteins, receptors, and enzymes[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.78mL 0.56mL 0.28mL |
13.88mL 2.78mL 1.39mL |
27.75mL 5.55mL 2.78mL |
