Temafloxacin

产品说明书

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Chemical Structure| 108319-06-8 同义名 : TMFX; TA-167 free acid; Omniflox; A-62254; A-62254 free acid
CAS号 : 108319-06-8
货号 : A720510
分子式 : C21H18F3N3O3
纯度 : 98+%
分子量 : 417.38
MDL号 : MFCD00864828
存储条件:

Pure form Keep in dark place, sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Temafloxacin is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.40mL

0.48mL

0.24mL

11.98mL

2.40mL

1.20mL

23.96mL

4.79mL

2.40mL

参考文献

[1]Rubinstein E. History of quinolones and their side effects. Chemotherapy. 2001;47 Suppl 3:3-8; discussion 44-8.

[2]Sorgel F, Naber KG, et al. Comparative pharmacokinetics of ciprofloxacin and temafloxacin in humans: a review. Am J Med. 1991 Dec 30;91(6A):51S-66S.