Grazoprevir hydrate

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Chemical Structure| 1350462-55-3 同义名 : MK-5172 hydrate
CAS号 : 1350462-55-3
货号 : A718868
分子式 : C38H52N6O10S
纯度 : 99+%
分子量 : 784.92
MDL号 : MFCD25976702
存储条件：

Pure form Sealed in dry, store in freezer, under -20°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.27mL

0.25mL

0.13mL

6.37mL

1.27mL

0.64mL

12.74mL

2.55mL

1.27mL
参考文献

[1]Summa V, Ludmerer SW, et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother. 2012 Aug;56(8):4161-7.