RI-2

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Chemical Structure| 1417162-36-7 同义名 : -
CAS号 : 1417162-36-7
货号 : A714632
分子式 : C21H18Cl2N2O4
纯度 : 98+%
分子量 : 433.28
MDL号 : MFCD28900748
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay and specifically inhibits HR (Homologous recombination) repair in human cells.
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

2.31mL

0.46mL

0.23mL

11.54mL

2.31mL

1.15mL

23.08mL

4.62mL

2.31mL
参考文献

[1]Budke B, Kalin JH, et al. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity. J Med Chem. 2013 Jan 10;56(1):254-63.