同义名 :	巨大戟二萜醇 ;(-)-Ingenol
	CAS号 :	30220-46-3
	货号 :	A689957
	分子式 :	C20H28O5
	纯度 :	99+%
	分子量 :	348.43
	MDL号 :	MFCD27980538
	存储条件：	Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月
	溶解度 :	-
	动物实验配方：

生物活性
描述	Ingenol is an extremely weak PKC (protein kinase C) activator and has been found to induce apoptosis and act as an anticancer agent.

临床研究
NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01541553	Actinic Keratosis	Phase 3	Completed	-	-
NCT02531295	HIV Human Imm... 展开 >>unodeficiency Virus 收起 <<	Phase 1	Recruiting	November 2020	United States, Utah ... 展开 >> University of Utah Recruiting Salt Lake City, Utah, United States, 84132 Contact: Adam M Spivak, MD    801-585-2031    adam.spivak@hsc.utah.edu    Contact: Zachary Mitchell    (801) 587-7467    zachary.mitchell@hsc.utah.edu    Principal Investigator: Sulggi A Lee, MD PhD          Principal Investigator: Adam M Spivak, MD          Sub-Investigator: Steven G Deeks, MD 收起 <<
NCT01541553	-		Completed	-	-

实验方案
	1mg	5mg	10mg
1 mM 5 mM 10 mM	2.87mL 0.57mL 0.29mL	14.35mL 2.87mL 1.44mL	28.70mL 5.74mL 2.87mL

参考文献
[1]Armstrong S, Ganote CE. Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia. Cardiovasc Res. 1994 Nov;28(11):1700-6. [2]Hasler CM, Acs G, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.