Penbutolol sulfate

产品说明书

Print
Chemical Structure| 38363-32-5 同义名 : (-)-Terbuclomine; Penbutolol(hemisulfate); HOE 39-893d; Penbutolol(sulfate)
CAS号 : 38363-32-5
货号 : A689026
分子式 : C36H60N2O8S
纯度 : 99%
分子量 : 680.94
MDL号 : N/A
存储条件:

Pure form Inert atmosphere, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月

溶解度 : -
动物实验配方:
生物活性
描述 Penbutolol sulfate is able to bind to both beta-1 adrenergic receptors and beta-2 adrenergic receptors (the two subtypes), thus making it a non-selective β blocker.
临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点
NCT01316952 - Completed - -
NCT00684489 Hypertension Not Applicable Completed - -
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.47mL

0.29mL

0.15mL

7.34mL

1.47mL

0.73mL

14.69mL

2.94mL

1.47mL

参考文献

[1]Ita KB, Popova IE. Influence of sonophoresis and chemical penetration enhancers on percutaneous transport of penbutolol sulfate. Pharm Dev Technol. 2016 Dec;21(8):990-995.

[2]Ita KB, Banga AK. In vitro transdermal iontophoretic delivery of penbutolol sulfate. Drug Deliv. 2009 Jan;16(1):11-4.