LLY-283
产品说明书
 |
同义名 : | - |
| CAS号 : | 2040291-27-6 | |
| 货号 : | A672444 | |
| 分子式 : | C17H18N4O4 | |
| 纯度 : | 99% | |
| 分子量 : | 342.35 | |
| MDL号 : | N/A | |
| 存储条件： |
Pure form Keep in dark place, inert atmosphere, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 22 nM and a Kd of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
2.92mL 0.58mL 0.29mL |
14.60mL 2.92mL 1.46mL |
29.21mL 5.84mL 2.92mL |
