UPGL00004

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Chemical Structure| 1890169-95-5 同义名 : -
CAS号 : 1890169-95-5
货号 : A670738
分子式 : C25H26N8O2S2
纯度 : 98%+
分子量 : 534.66
MDL号 : MFCD31812376
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 UPGL00004 is a potent, variant glutaminase C (GAC) inhibitor (IC50 = 29 nM; Kd = 27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines [1].The IC50 values of the inhibitory effects of UPGL00004 on MDA-MB-231, HS578T and TSE cells were 70 nM, 129 nM and 262 nM, respectively[1] .
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

1.87mL

0.37mL

0.19mL

9.35mL

1.87mL

0.94mL

18.70mL

3.74mL

1.87mL