GB-88
产品说明书
 |
同义名 : | - |
| CAS号 : | 1416435-96-5 | |
| 货号 : | A669532 | |
| 分子式 : | C32H42N4O4 | |
| 纯度 : | 99%+ | |
| 分子量 : | 546.7 | |
| MDL号 : | MFCD29920338 | |
| 存储条件： |
Pure form Sealed in dry, store in freezer, under -20°C In solvent -20°C:3-6个月-80°C:12个月 |
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| 溶解度 : | - | |
| 动物实验配方： |
| 生物活性 | |||
|---|---|---|---|
| 描述 | GB-88 is an orally active, selective non-peptide PAR2 antagonist that inhibits PAR2-activated Ca2+ release with an IC50 of 2 µM[1].GB-88 inhibits iCa2+ release induced by trypsin, 2f-LIGRLO-NH2 and GB110 (PAR2 agonist) in HT29 cells. The antagonistic effect of GB-88 is agonist dependent[1]. | ||
| 实验方案 | |||
|---|---|---|---|
| 1mg | 5mg | 10mg | |
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1 mM 5 mM 10 mM |
1.83mL 0.37mL 0.18mL |
9.15mL 1.83mL 0.91mL |
18.29mL 3.66mL 1.83mL |
