A-967079

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Chemical Structure| 1170613-55-4 同义名 : -
CAS号 : 1170613-55-4
货号 : A658572
分子式 : C12H14FNO
纯度 : 99%
分子量 : 207.24
MDL号 : MFCD20488058
存储条件：

Pure form Sealed in dry, 2-8°C

In solvent -20°C:3-6个月-80°C:12个月
溶解度 : -
动物实验配方：
生物活性
描述 A 967079 is a selective TRPA1 channel blocker (IC50 values are 67 and 289 nM at human and rat TRPA1 receptors respectively).
实验方案
1mg 5mg 10mg

1 mM

5 mM

10 mM

4.83mL

0.97mL

0.48mL

24.13mL

4.83mL

2.41mL

48.25mL

9.65mL

4.83mL
参考文献

[1]Chen J, Joshi SK, et al. Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain. 2011 May;152(5):1165-72.

[2]McGaraughty S, Chu KL, et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Mol Pain. 2010 Mar 5;6:14.